The sudden infant death syndrome (SIDS) is postulated to result from a failure of homeostatic
responses to life-threatening challenges (eg asphyxia, hypercapnia) during sleep. The …

Hypogonadism is the most common morbidity in patients with transfusion‐dependent
anemias such as thalassemia major. We used magnetic resonance imaging (MRI) to measure …

Immunotherapy is a promising area of therapy in patients with neuro-oncological malignancies.
However, early-phase studies show unique challenges associated with the assessment …

Magnetic resonance spectroscopy (MRS) offers a unique, noninvasive approach to assess
pediatric neurological abnormalities at microscopic levels by quantifying cellular metabolites. …

Deep neural networks are increasingly being used in both supervised learning for classification
tasks and unsupervised learning to derive complex patterns from the input data. However…

Background Paediatric low-grade glioma is the most common CNS tumour of childhood.
Although overall survival is good, disease often recurs. No single universally accepted …

Background Karen Ann Quinlan had a cardiopulmonary arrest in 1975 and died 10 years
later, having never regained consciousness. Her story prompted a national debate about the …

Purpose Diffuse brainstem gliomas (BSGs) and other high-grade gliomas (HGGs) of childhood
carry a dismal prognosis despite current treatments, and new therapies are needed. …

Between birth and late adolescence, the human brain undergoes exponential maturational
changes. Using in vivo magnetic resonance spectroscopy, we determined the developmental …

Magnetic resonance imaging (MRI) evaluation of the developing brain has dramatically
increased over the last decade. Faster acquisitions and the development of advanced MRI …