Response criteria for paediatric high-grade glioma vary historically and across different
cooperative groups. The Response Assessment in Neuro-Oncology working group developed …

… (B) Perfusion analysis is performed by placing an ROI on the enhancing mass in the perfusion
sequence (ROI #2, purple) and comparing it with the contralateral white matter (ROI #1, …

Background Paediatric low-grade glioma is the most common CNS tumour of childhood.
Although overall survival is good, disease often recurs. No single universally accepted …

Meningioma is the most common primary brain tumor. 1 With surgery being a primary mode
of therapy, minimally invasive alternatives to conventional open approaches to the resection …

Childhood posterior fossa (PF) ependymomas cause substantial morbidity and mortality.
These tumors lack recurrent genetic mutations, but a subset of these ependymomas exhibits …

… -KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway genes, or HK2 or PFKFB2,
was associated with poor overall prognosis independent of H3K27M status (Figures S2B–S2D…

… Using the relationship found in Figure 1, Figure 2B demonstrates the measured CBF as a
percentage of CBF predicted by oxygen content alone. The dotted line at 100% indicates when …

… (a, b) Axial diffusion-weighted MR image (a) and ADC map (b) at the level of the basal ganglia
show an acute infarct with restricted diffusion in the left basal ganglia and bilateral frontal …

Childhood posterior fossa group A ependymomas (PFAs) have limited treatment options and
bear dismal prognoses compared to group B ependymomas (PFBs). PFAs overexpress the …

Background. A specific form of small-vessel vasculopathy—cerebral microbleeds (CMBs)—has
been linked to various types of dementia in adults. We assessed the incidence of CMBs …