Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The ascending reticular activating system (ARAS) mediates arousal, an essential component
of human consciousness. Lesions of the ARAS cause coma, the most severe disorder of …

… We compare the whole, fixed brain data with data previously acquired (Edlow et al., 2012)
on a dissected brainstem–… Brian Edlow has no actual or potential conflicts of interest. …

… from the second scan, and CBF XeCT,BL is absolute CBF XeCT from the baseline scan. All
… administration for both baseline (Δt BL ) and intervention (Δt IN ) XeCT scans: rCBF DCS …

… Brian L Edlow , Brian L Edlow … Although our 16-patient sample was the largest to date that
has been studied with stimulus-based functional MRI and EEG in the ICU (Edlow et al., 2013), …

Objective: To characterize a brainstem location specific to coma-causing lesions, and its
functional connectivity network. Methods: We compared 12 coma-causing brainstem lesions to …

We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The
brain specimen was donated by a 58-year-old woman who had no history of neurological …

Emotions depend upon the integrated activity of neural networks that modulate arousal,
autonomic function, motor control, and somatosensation. Brainstem nodes play critical roles in …

“Diffuse correlation spectroscopy” (DCS) is a technology for non-invasive transcranial
measurement of cerebral blood flow (CBF) that can be hybridized with “near-infrared spectroscopy…

Every year, millions of brain magnetic resonance imaging (MRI) scans are acquired in hospitals
across the world. These have the potential to revolutionize our understanding of many …