The 2020 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for the
Secondary Prevention of Stroke includes current evidence-based recommendations and …

Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Compressive paleostresses, as recorded by twinned calcite in carbonate rocks that cover
cratonic northwestern North America, are perpendicular to the orogenic front of the Late …

The reduction in blood pressure seen with the use of beta-blocking drugs was an unexpected
finding. Initially there was resistance to their use as the reduction of cardiac output and …

Background Hashimoto encephalopathy is a rare form of encephalopathy thought to be of
autoimmune etiology. Cognitive changes and seizures are the most commonly reported …

BACKGROUND AND PURPOSE: The safety and efficacy of endovascular therapy for large-artery
stroke in the extended time window is not yet well-established. We performed a …

The utilization of 49 carbohydrates was examined for 134 isolates of Metarhizium anisopliae
covering 16 characterized strains, seven isolates of Metarhizium flavoviride var. flavoviride, …

Background Posterior reversible encephalopathy syndrome (PRES) is a clinical and
radiological entity characterized clinically by headache, altered mental status, seizures, visual …

Moxonidine is a centrally acting antihypertensive. Its action is mediated by imidazoline I 1
receptors located in the rostral ventro-lateral medulla (RVLM). Animal experiments show much …

Background Imidazoline I 1-receptor agonism represents a new mode of antihypertensive
action to inhibit peripheral α-adrenergic tone by a central mechanism. Adrenaline, …