Clopidogrel hyper-response and bleeding risk in neurointerventional procedures

C Goh, L Churilov, P Mitchell… - American Journal of …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Antiplatelet therapy is associated with decreased ischemic
events after neurointerventional procedures. Antiplatelet resistance negates the protective …

Measurement of antiplatelet inhibition during neurointerventional procedures: the effect of antithrombotic duration and loading dose

DJ Pandya, BFM Fitzsimmons, TJ Wolfe… - Journal of …, 2010 - Wiley Online Library
ABSTRACT BACKGROUND/OBJECTIVE Symptomatic thromboembolic events are the most
common complications associated with aneurysm coiling, and carotid and intracranial …

[HTML][HTML] Clopidogrel resistance by P2Y12 platelet function testing in patients undergoing neuroendovascular procedures: incidence of ischemic and hemorrhagic …

JD Nordeen, AV Patel, RM Darracott… - Journal of vascular …, 2013 - ncbi.nlm.nih.gov
Purpose: The purpose of the study was to assess clopidogrel resistance and whether
“intensified” antiplatelet therapy guided by platelet inhibition tests during neuroendovascular …

Platelet reactivity and hemorrhage risk in neurointerventional procedures under dual antiplatelet therapy

H Nishi, I Nakahara, S Matsumoto… - Journal of …, 2016 - jnis.bmj.com
Background and purpose Hemorrhagic complications during neurointerventional
procedures have various etiologies and can result in severe morbidity and mortality. This …

Platelet-function testing in patients undergoing neurovascular procedures: caught between a rock and a hard place

J Comin, DF Kallmes - American Journal of Neuroradiology, 2013 - Am Soc Neuroradiology
In the context of neurointerventional procedures, clopidogrel hyper-responsiveness has
been associated with hemorrhage; on the other hand, clopidogrel resistance has been …

Dual antiplatelet therapy monitoring for neurointerventional procedures using a point-of-care platelet function test: a single-center experience

DH Lee, A Arat, H Morsi, H Shaltoni… - American journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Growing evidence of the relationship between poor
antiplatelet response and occurrence of clinical events elicited the need of monitoring the …

Variability in initial response to standard clopidogrel therapy, delayed conversion to clopidogrel hyper-response, and associated thromboembolic and hemorrhagic …

JED Almandoz, Y Kadkhodayan, BM Crandall… - Journal of …, 2014 - jnis.bmj.com
Background and purpose Variability in response to clopidogrel therapy is increasingly being
recognized as an important factor in thromboembolic and hemorrhagic complications …

[HTML][HTML] Anti-platelet drug resistance in the prediction of thromboembolic complications after neurointervention

DS Ryu, CK Hong, YS Sim, CH Kim… - Journal of Korean …, 2010 - ncbi.nlm.nih.gov
Objective The aim of this study was to analyze the correlation between thromboembolic
complications and antiplatelet drugs before and after neurointervention. Methods Blood …

Influence of diabetes mellitus and cigarette smoking on variability of the clopidogrel-induced antiplatelet effect and efficacy of active management of the target P2Y12 …

I Nakagawa, HS Park, S Yokoyama, T Wada… - Journal of Stroke and …, 2016 - Elsevier
Background Optimal antiplatelet inhibition is essential in patients undergoing
neurointerventional procedures; however, variability in response to clopidogrel can …

The roles and issues of P2Y12 percent inhibition assessed by VerifyNow assay for patients undergoing neurointervention: a prospective study

D Kashiwazaki, N Kuwayama, N Akioka… - Journal of Stroke and …, 2014 - Elsevier
Background Antiplatelet agents have an important role in the prevention of ischemic
complications during endovascular treatment. The aim of this study was to identify …