Tethered cord syndrome (TCS) is a clinical condition of various origins that arises from
tension on the spinal cord. Radiographic findings may include the conus medullaris in a lower …

Brain tumors are the fifth leading cause of cancer-related death in women ages 20 to 39 years.
Although the presentation of intracranial tumors during pregnancy is relatively uncommon…

Increasing evidence points to a fundamental role for cancer stem cells (CSC) in the initiation
and propagation of many tumors. As such, in the context of glioblastoma multiforme (GBM), …

Medulloblastoma (MB) is the most common malignant childhood brain tumour 1 , 2 , yet the
origin of the most aggressive subgroup-3 form remains elusive, impeding development of …

Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis pediatric brain tumor. No effective
curative therapy is currently available and no therapeutic advances have been made in …

OBJECTIVE With the objective of investigating the utility of CXCR4, a chemokine receptor
known to mediate glioma cell invasiveness, as a molecular marker for peritumoral disease …

The prognosis for patients with malignant glioma, which is the most common primary intracranial
neoplasm, remains dismal despite significant progress in neurooncological therapies …

Purpose Cyclin-dependent kinase-retinoblastoma (CDK-RB) pathway is dysregulated in some
diffuse intrinsic pontine gliomas (DIPG). We evaluated safety, feasibility, and early efficacy …

Colleges and universities are adopting learning communities to increase student learning
and build cohesion. As learning communities grow in popularity, institutions need to invest in …

Children with high-grade glioma, including diffuse intrinsic pontine glioma (DIPG), have a
poor prognosis despite multimodal therapy. Identifying novel therapeutic targets is critical to …