User profiles for C.C. Quarles

Chad Quarles

Professor, Cancer Systems Imaging
Verified email at mdanderson.org
Cited by 2989

Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas

JL Boxerman, CC Quarles, LS Hu, BJ Erickson… - Neuro …, 2020 - academic.oup.com
Despite the widespread clinical use of dynamic susceptibility contrast (DSC) MRI, DSC-MRI
methodology has not been standardized, hindering its utilization for response assessment in …

Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS …

…, JL Boxerman, TJ Kaufmann, CC Quarles… - Neuro …, 2021 - academic.oup.com
… a power injector is desirable at an injection rate of 3-5 cc/sec. … a power injector is desirable
at an injection rate of 3-5 cc/sec. … a power injector is desirable at an injection rate of 3-5 cc/sec. …

Quantitative multimodality imaging in cancer research and therapy

…, RG Abramson, CC Quarles - Nature Reviews Clinical …, 2014 - nature.com
Advances in hardware and software have enabled the realization of clinically feasible,
quantitative multimodality imaging of tissue pathophysiology. Earlier efforts relating to …

Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

…, KA Smith, P Nakaji, JP Karis, CC Quarles… - Neuro …, 2017 - academic.oup.com
Background Glioblastoma (GBM) exhibits profound intratumoral genetic heterogeneity. Each
tumor comprises multiple genetically distinct clonal populations with different therapeutic …

Imaging vascular and hemodynamic features of the brain using dynamic susceptibility contrast and dynamic contrast enhanced MRI

CC Quarles, LC Bell, AM Stokes - Neuroimage, 2019 - Elsevier
In the context of neurologic disorders, dynamic susceptibility contrast (DSC) and dynamic
contrast enhanced (DCE) MRI provide valuable insights into cerebral vascular function, …

Improving the reliability of obtaining tumor hemodynamic parameters in the presence of contrast agent extravasation

CC Quarles, BD Ward… - Magnetic Resonance in …, 2005 - Wiley Online Library
A new approach to improve the reliability of dynamic susceptibility contrast MRI for the
evaluation of brain tumor hemodynamics in the presence of contrast agent extravasation is …

Magnetic resonance in the era of molecular imaging of cancer

JC Gore, HC Manning, CC Quarles, KW Waddell… - Magnetic resonance …, 2011 - Elsevier
Magnetic resonance imaging (MRI) has played an important role in the diagnosis and
management of cancer since it was first developed, but other modalities also continue to advance …

[HTML][HTML] Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors

…, R Perryman, J Symington, CC Quarles… - The Journal of …, 2022 - Am Soc Clin Investig
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical
need. Here, we illustrate that the efficacy of radiotherapy for GBM is strikingly potentiated …

A theoretical framework to model DSC-MRI data acquired in the presence of contrast agent extravasation

CC Quarles, DF Gochberg, JC Gore… - Physics in Medicine & …, 2009 - iopscience.iop.org
Dynamic susceptibility contrast (DSC) MRI methods rely on compartmentalization of the
contrast agent such that a susceptibility gradient can be induced between the contrast-…

Comparison of dual-echo DSC-MRI-and DCE-MRI-derived contrast agent kinetic parameters

CC Quarles, JC Gore, L Xu, TE Yankeelov - Magnetic resonance imaging, 2012 - Elsevier
The application of dynamic susceptibility contrast (DSC) MRI methods to assess brain tumors
is often confounded by the extravasation of contrast agent (CA). Disruption of the blood–…