Axial motor signs—including gait impairment, postural instability and postural abnormalities—are
common and debilitating symptoms in patients with advanced Parkinson disease. …

In this review, the available evidence to guide clinicians regarding eligibility for deep brain
stimulation (DBS) in the main conditions in which these forms of therapy are generally …

Background Deep brain stimulation (DBS) of the subcallosal cingulate white matter has
shown promise as an intervention for patients with chronic, unremitting depression. To test the …

Object Deep brain stimulation (DBS) has been recently investigated as a treatment for major
depression. One of the proposed targets for this application is the subcallosal cingulate …

Object. Aquaporin-4 (AQP4) plays a significant role in the regulation of brain water homeostasis.
In this study the authors investigated the regulation of AQP4 following a focal cortical …

Human retinal pigment epithelial (hRPE) cells are dopaminergic support cells in the neural
retina. Stereotaxic intrastriatal implantation of hRPE cells attached to gelatin microcarriers (…

OBJECTIVE: Hypomania accounts for approximately 4% to 13% of psychotropic adverse
events during subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease. …

2658 Reducing - Honey Page 1 194 CME Choice During the last decade many new options
have become available for the surgical treatment of movement disorders. The development …

To determine whether the degree to which a patient with Parkinson's disease expects
therapeutic benefit from subthalamic nucleus–deep brain stimulation (STN‐DBS) influences the …

Excitatory amino acids depolarize central mammalian neurons by increasing membrane
conductance. This increase in conductance can be voltage-dependent (ie N-methyl-d-aspartate …