BAY 43-9006: preclinical data
S Wilhelm, DS Chien - Current pharmaceutical design, 2002 - ingentaconnect.com
The drug design and discovery efforts described in the previous section led to the development
of a novel, small molecule Raf-1 kinase inhibitor, BAY 43-9006, which belongs to a class …
of a novel, small molecule Raf-1 kinase inhibitor, BAY 43-9006, which belongs to a class …
Tumor cell vascular mimicry: Novel targeting opportunity in melanoma
…, EA Seftor, REB Seftor, JT Chao, DS Chien… - Pharmacology & …, 2016 - Elsevier
… Tumor cell vasculogenic mimicry (VM), also known as vascular mimicry, describes the
plasticity of aggressive cancer cells forming de novo vascular networks and is associated with the …
plasticity of aggressive cancer cells forming de novo vascular networks and is associated with the …
[HTML][HTML] Associations and dynamics of Vibrionaceae in the environment, from the genus to the population level
The Vibrionaceae, which encompasses several potential pathogens, including V. cholerae,
the causative agent of cholera, and V. vulnificus, the deadliest seafood-borne pathogen, are …
the causative agent of cholera, and V. vulnificus, the deadliest seafood-borne pathogen, are …
Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration
W Wang, H Sasaki, DS Chien, VHL Lee - Current eye research, 1991 - Taylor & Francis
The influence of lipophilicity on the conjunctival penetration of beta blockers in the pigmented
rabbit was investigated and compared with that on corneal penetration. The beta blockers …
rabbit was investigated and compared with that on corneal penetration. The beta blockers …
Corneal and conjunctival/scleral penetration of p-aminoclonidine, AGN 190342, and clonidine in rabbit eyes
DS Chien, JJ Homsy, C Gluchowski… - Current eye …, 1990 - Taylor & Francis
… d i ne and p-ami nocl oni d i ne in most ocular tissues. The total tissue drug concentrations
absorbed via the corneal and conjunctival/scleral routes followed a different rank order …
absorbed via the corneal and conjunctival/scleral routes followed a different rank order …
Fast magnetic resonance diffusion‐weighted imaging of acute human stroke
S Warach, D Chien, W Li, M Ronthal, RR Edelman - Neurology, 1992 - AAN Enterprises
Rapid MRI of the molecular diffusion of water demonstrated cerebral infarcts in 32 patients.
We studied these patients at various times following the onset of ischemic symptoms and …
We studied these patients at various times following the onset of ischemic symptoms and …
Vaccination of chimpanzees against infection by the hepatitis C virus.
…, G Kuo, R Ralston, A Weiner, D Chien… - Proceedings of the …, 1994 - National Acad Sciences
A high incidence of community-acquired hepatitis C virus infection that can lead to the
progressive development of chronic active hepatitis, liver cirrhosis, and primary hepatocellular …
progressive development of chronic active hepatitis, liver cirrhosis, and primary hepatocellular …
Fast selective black blood MR imaging.
RR Edelman, D Chien, D Kim - Radiology, 1991 - pubs.rsna.org
To overcome the problems associated with gradient-echo (GRE) magnetic resonance (MR)
angiography ("bright blood" imaging) and "black blood" imaging with presaturated spin-echo …
angiography ("bright blood" imaging) and "black blood" imaging with presaturated spin-echo …
[PDF][PDF] The aggressive victim of bullying
D Schwartz, LJ Proctor, DH Chien - … in school: The plight of the …, 2001 - stopsuicide.ch
Theoretical perspectives on bully/victim problems often incorporate a conceptualization of
the persistently targeted child as submissive, inhibited, or socially withdrawn (Perry, Perry, & …
the persistently targeted child as submissive, inhibited, or socially withdrawn (Perry, Perry, & …
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807
DT Chien, S Bahri, AK Szardenings… - Journal of …, 2013 - content.iospress.com
Aggregates of hyperphosphorylated tau (PHF-tau), such as neurofibrillary tangles, are linked
to the degree of cognitive impairment in Alzheimer's disease. We have developed a novel …
to the degree of cognitive impairment in Alzheimer's disease. We have developed a novel …