User profiles for D L Daniels
Danette DanielsGroup Leader, Promega Corporation Verified email at promega.com Cited by 6862 |
Pictorial review of glutamate excitotoxicity: fundamental concepts for neuroimaging
…, JL Ulmer, MM Smith, DL Daniels… - American journal …, 2001 - Am Soc Neuroradiology
Neuroradiologists may encounter, on a daily basis, a challenging diversity of neurologic
disorders, including stroke, trauma, epilepsy, and even neurodegenerative conditions, such as …
disorders, including stroke, trauma, epilepsy, and even neurodegenerative conditions, such as …
The ascending pharyngeal artery: branches, anastomoses, and clinical significance
L Hacein-Bey, DL Daniels, JL Ulmer… - American Journal …, 2002 - Am Soc Neuroradiology
Neuroradiologists generally do not fully appreciate the importance of the territory of the
ascending pharyngeal artery. The ascending pharyngeal artery is a small but important artery …
ascending pharyngeal artery. The ascending pharyngeal artery is a small but important artery …
β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
DL Daniels, WI Weis - Nature structural & molecular biology, 2005 - nature.com
Wnt growth factors mediate cell fate determination during embryogenesis and in the renewal
of tissues in the adult. Wnts act by stabilizing cellular levels of the transcriptional coactivator …
of tissues in the adult. Wnts act by stabilizing cellular levels of the transcriptional coactivator …
The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation
Targeted protein degradation has exploded over the past several years due to preclinical
and early clinical therapeutic success of numerous compounds, and the emergence of new …
and early clinical therapeutic success of numerous compounds, and the emergence of new …
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
…, T Mercher, E Solary, M Urh, DL Daniels… - The EMBO …, 2013 - embopress.org
TET proteins convert 5‐methylcytosine to 5‐hydroxymethylcytosine, an emerging dynamic
epigenetic state of DNA that can influence transcription. Evidence has linked TET1 function to …
epigenetic state of DNA that can influence transcription. Evidence has linked TET1 function to …
NanoBRET A Novel BRET Platform for the Analysis of Protein–Protein Interactions
…, K Zimmerman, P Otto, DL Daniels… - ACS chemical …, 2015 - ACS Publications
Dynamic interactions between proteins comprise a key mechanism for temporal control of
cellular function and thus hold promise for development of novel drug therapies. It remains …
cellular function and thus hold promise for development of novel drug therapies. It remains …
[PDF][PDF] ICAT inhibits β-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules
DL Daniels, WI Weis - Molecular cell, 2002 - cell.com
In the canonical Wnt signaling pathway, β-catenin activates target genes through its interactions
with Tcf/Lef-family transcription factors and additional transcriptional coactivators. The …
with Tcf/Lef-family transcription factors and additional transcriptional coactivators. The …
[HTML][HTML] HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia
…, X Wang, MK Schwinn, B Qin, HW Long, DL Daniels… - Cell, 2013 - cell.com
The transcription factor HIF1A is a key mediator of the cellular response to hypoxia. Despite
the importance of HIF1A in homeostasis and various pathologies, little is known about how it …
the importance of HIF1A in homeostasis and various pathologies, little is known about how it …
Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
DL Daniels, AR Cohen, JM Anderson… - Nature structural …, 1998 - nature.com
PDZ domain containing proteins assist formation of cell–cell junctions and localization of
membrane protein receptors and ion channels. PDZ domains interact with the C-terminal …
membrane protein receptors and ion channels. PDZ domains interact with the C-terminal …
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
Bivalent proteolysis-targeting chimeras (PROTACs) drive protein degradation by simultaneously
binding a target protein and an E3 ligase and forming a productive ternary complex. We …
binding a target protein and an E3 ligase and forming a productive ternary complex. We …