Mouse models are useful for studying genes involved in behavior, but whether they are
relevant to human behavior is unclear. Here, we identified parallel phenotypes in mice and …

Osteoarthritis and avascular necrosis are common clinical entities with unknown origins.
Recently, vascular changes were implicated in the pathogenesis of both conditions. This article …

We used diffusion tensor imaging (DTI) to study 2 patients with traumatic brain injury. The
first patient recovered reliable expressive language after 19 years in a minimally conscious …

OBJECTIVE. The purpose of this study was to analyze features of breast lesions detected
on MR imaging that had subsequent biopsy and to determine the positive predictive value (PPV…

OBJECTIVE. The purpose of this study was to determine the frequency of cancer and the
positive predictive value of biopsy in the first screening round of breast MRI in women at high …

Late infantile neuronal ceroid lipofuscinosis (LINCL) is an autosomal recessive, neurodegenerative
lysosomal storage disease affecting the CNS and is fatal by age 8 to 12 years. A total …

Background Recombinant human tripeptidyl peptidase 1 (cerliponase alfa) is an enzyme-replacement
therapy that has been developed to treat neuronal ceroid lipofuscinosis type 2 (…

Functional neuroimaging methods hold promise for the identification of cognitive function
and communication capacity in some severely brain-injured patients who may not retain …

… (D) Quantification of p75NTR expression level in postnatal mouse hippocampi at different
ages indicated (three hippocampi per genotye). ns, p > 0.05. (E) Secretion of proBDNF-HA …

… Every transformant expressing Sst2-N-UbG and Ste2-C-Ub-LV showed robust reporter-gene
expression at a level equivalent to that of the positive control (Figure 4D). For this control, …