User profiles for D. Brenner

David A. Brenner

Vice Chancellor of Health Sciences
Verified email at ucsd.edu
Cited by 91729

[HTML][HTML] Liver fibrosis

R Bataller, DA Brenner - The Journal of clinical investigation, 2005 - Am Soc Clin Investig
Liver fibrosis is the excessive accumulation of extracellular matrix proteins including
collagen that occurs in most types of chronic liver diseases. Advanced liver fibrosis results in …

Computed tomography—an increasing source of radiation exposure

DJ Brenner, EJ Hall - New England journal of medicine, 2007 - Mass Medical Soc
The number of computed tomographic (CT) studies performed is increasing rapidly. Because
CT scans involve much higher doses of radiation than plain films, we are seeing a marked …

[HTML][HTML] Liver inflammation and fibrosis

Y Koyama, DA Brenner - The Journal of clinical …, 2017 - Am Soc Clin Investig
Chronic liver inflammation leads to fibrosis and cirrhosis, which is the 12th leading cause of
death in the United States. Hepatocyte steatosis is a component of metabolic syndrome and …

Cancer risks attributable to low doses of ionizing radiation: assessing what we really know

DJ Brenner, R Doll, DT Goodhead… - Proceedings of the …, 2003 - National Acad Sciences
High doses of ionizing radiation clearly produce deleterious consequences in humans,
including, but not exclusively, cancer induction. At very low radiation doses the situation is much …

Estimated risks of radiation-induced fatal cancer from pediatric CT

DJ Brenner, CD Elliston, EJ Hall… - American journal of …, 2001 - Am Roentgen Ray Soc
OBJECTIVE. In light of the rapidly increasing frequency of pediatric CT examinations, the
purpose of our study was to assess the lifetime cancer mortality risks attributable to radiation …

TLR4 enhances TGF-β signaling and hepatic fibrosis

…, CH Österreicher, J Kluwe, Y Osawa, DA Brenner… - Nature medicine, 2007 - nature.com
Hepatic injury is associated with a defective intestinal barrier and increased hepatic exposure
to bacterial products. Here we report that the intestinal bacterial microflora and a functional …

[BOOK][B] Theory of multivariate statistics

M Bilodeau, D Brenner - 1999 - books.google.com
Our object in writing this book is to present the main results of the modern theory of multivariate
statistics to an audience of advanced students who would appreciate a concise and …

Prolonged activation of jun and collagenase genes by tumour necrosis factor-α

DA Brenner, M O'Hara, P Angel, M Chojkier, M Karin - Nature, 1989 - nature.com
Tumour necrosis factor-α (TNF-α) is secreted by macrophages in response to inflammation,
infection and cancer 1 . Sublethal doses of recombinant TNF-α to rats causes cachexia, …

Estimated radiation risks potentially associated with full-body CT screening

DJ Brenner, CD Elliston - Radiology, 2004 - pubs.rsna.org
PURPOSE: To estimate the radiation-related cancer mortality risks associated with single or
repeated full-body computed tomographic (CT) examinations by using standard radiation …

Direct evidence that prostate tumors show high sensitivity to fractionation (low α/β ratio), similar to late-responding normal tissue

DJ Brenner, AA Martinez, GK Edmundson… - International Journal of …, 2002 - Elsevier
Purpose : A direct approach to the question of whether prostate tumors have an atypically
high sensitivity to fractionation (low α/β ratio), more typical of the surrounding late-responding …