WHO 2016 Classification of gliomas

P Wesseling, D Capper - Neuropathology and applied …, 2018 - Wiley Online Library
… Dr Capper reports receiving income from two patents held by the German Cancer Research
Center (DKFZ): one for an antibody to detect R132H-mutant IDH1 in fixed glioma samples, …

cIMPACT‐NOW update 7: advancing the molecular classification of ependymal tumors

DW Ellison, KD Aldape, D Capper, M Fouladi… - Brain …, 2020 - Wiley Online Library
Advances in our understanding of the biological basis and molecular characteristics of
ependymal tumors since the latest iteration of the World Health Organization (WHO) classification …

Brain metastases: pathobiology and emerging targeted therapies

M Preusser, D Capper, A Ilhan-Mutlu, AS Berghoff… - Acta …, 2012 - Springer
Brain metastases (BM) are common in cancer patients and are associated with high
morbidity and poor prognosis, even after intensive multimodal therapy including resection, …

DNA methylation-based classification of central nervous system tumours

D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf… - Nature, 2018 - nature.com
Accurate pathological diagnosis is crucial for optimal management of patients with cancer.
For the approximately 100 known tumour types of the central nervous system, standardization …

The impact of conservation on the status of the world's vertebrates

…, W Bolivar-G, IJ Burfield, JA Burton, DR Capper… - science, 2010 - science.org
Using data for 25,780 species categorized on the International Union for Conservation of
Nature Red List, we present an assessment of the status of the world’s vertebrates. One-fifth of …

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

…, G Dharmalingam, AP Snijders, T Carroll, D Capper… - Nature cell …, 2013 - nature.com
… (d) Normal HMEC or IMR90 cells suffer growth arrest when co-cultured with HMEC cells
undergoing OIS. HMEC TERT (centre) or IMR90 (right) cells expressing Cherry as a fluorescent …

[PDF][PDF] Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups

…, M Ryzhova, S Mack, V Ramaswamy, D Capper… - Cancer cell, 2015 - cell.com
Ependymal tumors across age groups are currently classified and graded solely by histopathology.
It is, however, commonly accepted that this classification scheme has limited clinical …

The whole-genome landscape of medulloblastoma subtypes

…, SJM Jones, O Witt, T Milde, A Von Deimling, D Capper… - Nature, 2017 - nature.com
Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose
debilitating effects on the developing child, and highlight the need for molecularly targeted …

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra …

G Schindler, D Capper, J Meyer, W Janzarik… - Acta …, 2011 - Springer
… Six of the PXA II samples in this study are also included in a separate study by D. Dias-… the
presence of BRAF V600E was significantly associated with younger patient age (d; p = 0.001) …

[PDF][PDF] New brain tumor entities emerge from molecular classification of CNS-PNETs

…, UH Toprak, V Hovestadt, DTW Jones, D Capper… - Cell, 2016 - cell.com
Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly
aggressive, poorly differentiated embryonal tumors occurring predominantly in young children …