A concerted effort to tackle the global health problem posed by traumatic brain injury (TBI) is
long overdue. TBI is a public health challenge of vast, but insufficiently recognised, …

Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Endovascular treatment is a highly effective therapy for acute ischemic stroke due to large
vessel occlusion and has recently revolutionized stroke care. Oftentimes, ischemic core extent …

Background In patients with acute ischemic stroke caused by a proximal intracranial arterial
occlusion, intraarterial treatment is highly effective for emergency revascularization. However…

Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

Importance Endovascular thrombectomy with second-generation devices is beneficial for
patients with ischemic stroke due to intracranial large-vessel occlusions. Delineation of the …

Endovascular therapy (EVT) for acute ischemic stroke in selected patients has recently been
proven effective in several clinical trials, and the widespread adoption of thrombectomy into …

Background The value of administering intravenous alteplase before endovascular treatment
(EVT) for acute ischemic stroke has not been studied extensively, particularly in non-Asian …

Background The effectiveness of endovascular therapy in patients with stroke caused by
basilar-artery occlusion has not been well studied. Methods We randomly assigned patients …

Background In acute ischemic stroke, there is uncertainty regarding the benefit and risk of
administering intravenous alteplase before endovascular thrombectomy. Methods We …