… In the striatum, ERK1/2 activation in response to D-amphetamine occurs in a subset of γ-…
responses to cocaine, D-amphetamine or THC are prevented by N-methyl-d-aspartate (NMDA) …

… (c–e’) EGFP fluorescence alone (green; c, d and e) or combined with DARPP-32 immunoreactivity
(red; c’, d’ and e’), which labels all medium-sized spiny neurons in drd1a–EGFP (c, c’)…

Fibromuscular dysplasia is an uncommon, segmental, nonatherosclerotic arterial disease of
unknown aetiology. The disease primarily affects women and involves intermediate-sized …

Background The effect of personalised mechanical ventilation on clinical outcomes in
patients with acute respiratory distress syndrome (ARDS) remains uncertain and needs to be …

… Here, we show in mouse that d-amphetamine activates ERK in a subset of medium-size
spiny neurons of the dorsal striatum and nucleus accumbens, through the combined action of …

… stimulation of dopamine D 1 receptors (D1Rs) and glutamate NMDA receptors. Antipsychotic
drugs activate similar signaling proteins in the striatum by blocking dopamine D 2 receptors …

… (d) Changes in the BRET ratio from basal signal to maximal response (R max ) that reflect
the amplitude of the response. (e) Analysis of the expression of Gα olf and Gβγ (detected by …

In the brain, dopamine and adenosine stimulate cyclic AMP (cAMP) production through D1
and A2a receptors, respectively. Using mutant mice deficient in the olfactory isoform of the …

The molecular basis of l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia (LID), one
of the major hindrances in the current therapy for Parkinson's disease, is still unclear. We …

A major goal of research on addiction is to identify the molecular mechanisms of long‐lasting
behavioural alterations induced by drugs of abuse. Cocaine and delta‐9‐…