Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
…, SB Coutts, D Roy, JL Rempel, ACR Rohr, D Iancu… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
Optimality of affine policies in multistage robust optimization
D Bertsimas, DA Iancu… - Mathematics of Operations …, 2010 - pubsonline.informs.org
In this paper, we prove the optimality of disturbance-affine control policies in the context of
one-dimensional, constrained, multistage robust optimization. Our results cover the finite-…
one-dimensional, constrained, multistage robust optimization. Our results cover the finite-…
Pareto efficiency in robust optimization
DA Iancu, N Trichakis - Management Science, 2014 - pubsonline.informs.org
This paper formalizes and adapts the well-known concept of Pareto efficiency in the context
of the popular robust optimization (RO) methodology for linear optimization problems. We …
of the popular robust optimization (RO) methodology for linear optimization problems. We …
Supermodularity and affine policies in dynamic robust optimization
This paper considers a particular class of dynamic robust optimization problems, where a
large number of decisions must be made in the first stage, which consequently fix the …
large number of decisions must be made in the first stage, which consequently fix the …
[HTML][HTML] Reviewing the research on instructional development programs for academics. Trying to tell a different story: A meta-analysis
This paper presents a meta-analysis that investigates the effectiveness of instructional
development programs (IDPs) dedicated to academics. IDPs are instructional activities specifically …
development programs (IDPs) dedicated to academics. IDPs are instructional activities specifically …
Disruption risk and optimal sourcing in multitier supply networks
We study sourcing in a supply chain with three levels: a manufacturer, tier 1 suppliers, and
tier 2 suppliers prone to disruption from, eg, natural disasters such as earthquakes or floods. …
tier 2 suppliers prone to disruption from, eg, natural disasters such as earthquakes or floods. …
A hierarchy of near-optimal policies for multistage adaptive optimization
D Bertsimas, DA Iancu… - IEEE Transactions on …, 2011 - ieeexplore.ieee.org
… For a fixed polynomial degree d, we develop a convex reformulation of the constraints
and objective of the problem, using Sums-Of-Squares (SOS) techniques. In the resulting …
and objective of the problem, using Sums-Of-Squares (SOS) techniques. In the resulting …
EAST syndrome: Clinical, pathophysiological, and genetic aspects of mutations in KCNJ10
…, D Iancu, H Stanescu, R Kleta, D Bockenhauer - Rare …, 2016 - Taylor & Francis
EAST syndrome is a recently described autosomal recessive disorder secondary to mutations
in KCNJ10 (Kir4.1), a gene encoding a potassium channel expressed in the brain, eye, …
in KCNJ10 (Kir4.1), a gene encoding a potassium channel expressed in the brain, eye, …
Robust multistage decision making
Testifying to more than 10 years of academic and practical developments, this tutorial attempts
to provide a succinct yet unified view of the robust multistage decision-making framework. …
to provide a succinct yet unified view of the robust multistage decision-making framework. …
Sleep patterns in autistic children
E Hering, R Epstein, S Elroy, DR Iancu… - Journal of autism and …, 1999 - Springer
Sleep disturbances are regarded as a common clinical feature in autistic children. This concept
is based primarily on informal observations or studies conducted with questionnaires. In …
is based primarily on informal observations or studies conducted with questionnaires. In …