After completion of this article, the reader will be able to 1) state the therapeutic interventions
that are currently used to treat intraocular retinoblastoma, and to outline the mechanism of …

Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …

Retinoblastoma has gone from >95% mortality to >95% survival in the past 100 years. Once
enucleation techniques were perfected, the majority of children survived, but without the eye …

OBJECTIVE: To develop a technique that would allow us to cannulate repeatedly the ophthalmic
artery of young children with advanced retinoblastoma, to find a dose of melphalan that …

A review of 693 patients with bilateral retinoblastoma and 18 patients with unilateral/germinal
retinoblastoma was carried out to find the incidence, time, course and pattern of second …

OBJECTIVE: This study aimed to investigate the relationship in bilateral retinoblastoma
survivors between the incidence of second tumors and the age when external beam radiation (…

A retrospective chart review was performed on the charts of 1265 patients with retinoblastoma
who were on file at New York Hospital and whose conditions had been diagnosed …

Context. —There is a substantial risk of a second cancer for persons with hereditary
retinoblastoma, which is enhanced by radiotherapy. Objective. —To examine long-term risk of new …

PURPOSE: To evaluate the efficacy and toxicity of subconjunctival carboplatin for
intraocular retinoblastoma. DESIGN: A phase I/II clinical trial (noncomparative case series). …

Objective. To correlate 3 common presenting signs of retinoblastoma with patient and ocular
survival and to assess the efficacy of current pediatric screening practices for retinoblastoma…