User profiles for D.L. Arnold
 | Douglas Lorne Arnold, MD, FRCP(C)James McGill Professor: Department of Neurology and Neurosurgery, Faculty of Medicine … Verified email at mcgill.ca Cited by 57702 |
Review of automatic segmentation methods of multiple sclerosis white matter lesions on conventional magnetic resonance imaging
Magnetic resonance (MR) imaging is often used to characterize and quantify multiple sclerosis
(MS) lesions in the brain and spinal cord. The number and volume of lesions have been …
(MS) lesions in the brain and spinal cord. The number and volume of lesions have been …
Standardized MR imaging protocol for multiple sclerosis: Consortium of MS Centers consensus guidelines
…, A Traboulsee, PK Coyle, DL Arnold… - American Journal …, 2006 - Am Soc Neuroradiology
MR imaging has played an important role in contributing to our understanding of the natural
history of multiple sclerosis (MS) in the brain and spinal cord, including its expression as …
history of multiple sclerosis (MS) in the brain and spinal cord, including its expression as …
Secondary progressive multiple sclerosis: new insights
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[HTML][HTML] B-cell depletion with rituximab in relapsing–remitting multiple sclerosis
Background There is increasing evidence that B lymphocytes are involved in the pathogenesis
of multiple sclerosis, and they may be a therapeutic target. Rituximab, a monoclonal …
of multiple sclerosis, and they may be a therapeutic target. Rituximab, a monoclonal …
[HTML][HTML] Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis
Background BG-12 (dimethyl fumarate) was shown to have antiinflammatory and cytoprotective
properties in preclinical experiments and to result in significant reductions in disease …
properties in preclinical experiments and to result in significant reductions in disease …
[HTML][HTML] Ocrelizumab versus placebo in primary progressive multiple sclerosis
Background An evolving understanding of the immunopathogenesis of multiple sclerosis
suggests that depleting B cells could be useful for treatment. We studied ocrelizumab, a …
suggests that depleting B cells could be useful for treatment. We studied ocrelizumab, a …
[HTML][HTML] Ocrelizumab versus interferon beta-1a in relapsing multiple sclerosis
…, A Traboulsee, JS Wolinsky, DL Arnold… - … England Journal of …, 2017 - Mass Medical Soc
Background B cells influence the pathogenesis of multiple sclerosis. Ocrelizumab is a humanized
monoclonal antibody that selectively depletes CD20+ B cells. Methods In two identical …
monoclonal antibody that selectively depletes CD20+ B cells. Methods In two identical …
Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial
Background The anti-CD52 monoclonal antibody alemtuzumab reduced disease activity in a
phase 2 trial of previously untreated patients with relapsing-remitting multiple sclerosis. We …
phase 2 trial of previously untreated patients with relapsing-remitting multiple sclerosis. We …
Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial
Background The anti-CD52 monoclonal antibody alemtuzumab reduces disease activity in
previously untreated patients with relapsing-remitting multiple sclerosis. We aimed to assess …
previously untreated patients with relapsing-remitting multiple sclerosis. We aimed to assess …
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy
… Preul, MC, Collins, DL, & Arnold, DL Differential diagnosis of human intracranial tumours
in vivo using "H-MR spectroscopic imaging and feature space for spectral pattern recognition. …
in vivo using "H-MR spectroscopic imaging and feature space for spectral pattern recognition. …
