Background. The President’s Commission for the Study of Ethical Problems in Medicine and
Biomedical and Behavioral Research15 defined “brain death” as irreversible cessation of …

Objective: To provide an update of the 1995 American Academy of Neurology guideline with
regard to the following questions: Are there patients who fulfill the clinical criteria of brain …

… We read with interest the recent article by Wijdicks [1] and the accompanying editorial [2]
comparing brain death criteria worldwide. The article implies a universal acceptance of this …

Purpose— Our goal is to provide an overview of the current evidence about components of
the evaluation and treatment of adults with acute ischemic stroke. The intended audience is …

Objective: To systematically review outcomes in comatose survivors after cardiac arrest and
cardiopulmonary resuscitation (CPR). Methods: The authors analyzed studies (1966 to 2006…

The Glasgow Coma Scale (GCS) has been widely adopted. Failure to assess the verbal
score in intubated patients and the inability to test brainstem reflexes are shortcomings. We …

… of data: Lee, Wijdicks, Manno, and Rabinstein. Drafting of the manuscript: Lee and Wijdicks.
Critical revision of the manuscript for important intellectual content: Wijdicks, Manno, and …

This review summarizes recent changes in the treatment of adults with community-acquired
bacterial meningitis. It explains the initial assessment and management, the use of …

Physicians, health care workers, members of the clergy, and laypeople throughout the world
have accepted fully that a person is dead when his or her brain is dead. In the United States…

Generalized myoclonus status is common in comatose patients after cardiac resuscitation,
but its prognostic value is uncertain. We studied the clinical, radiologic, and pathologic …