BACKGROUND AND PURPOSE: Early assignment of disease progression among patients
with X-linked adrenoleukodystrophy (ALD) is critical for the appropriate selection of effective …

BACKGROUND AND PURPOSE: Quantitative MR imaging techniques may improve the
pathologic specificity of MR imaging regarding white matter abnormalities. Our purposes …

Background: X-linked adrenoleukodystrophy (X-ALD) has variants with widely different
outcomes, hampering clinical counseling and evaluation of therapies. Objective: To evaluate …

Background An inherited disorder, X-linked adrenoleukodystrophy (X-ALD) is known to
cause progressive inflammatory demyelination. Objective To analyze the adult pattern of …

PURPOSE: To compare conventional magnetic resonance (MR) imaging, proton MR
spectroscopic imaging, and diffusion tensor (DT) MR imaging findings in patients with X …

Background: The phenotypic expression of X-linked adrenoleukodystrophy (X-ALD) ranges
from the rapidly progressive childhood cerebral form to the milder adrenomyeloneuropathy …

Background Adults with X-linked adrenoleukodystrophy (X-ALD) remain at risk for
progressive neurological deterioration. Phenotypes vary in their pathology, ranging from …

X-linked adrenoleukodystrophy (ALD) is a rare metabolic disorder caused by peroxisomal
enzyme failure. Several phenotypes can be distinguished on the basis of clinical onset and …

PURPOSE To develop a scoring method for brain observations in patients with X-linked
adrenoleukodystrophy. METHODS One hundred seventy-five brain MR scans in 83 male …

The cerebral phenotype of X-linked adrenoleukodystrophy (ALD) is a rapidly progressive
neurodegenerative disorder characterized by a cerebral inflammatory response and …