Apparent diffusion coefficients in spinal cord transplants and surrounding white matter correlate with degree of axonal dieback after injury in rats

ED Schwartz, CL Chin, JS Shumsky… - American journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Abnormal apparent diffusion coefficient (ADC) values in
injured spinal cord white matter and fibroblast transplants have been shown to correspond …

Ex vivo MR determined apparent diffusion coefficients correlate with motor recovery mediated by intraspinal transplants of fibroblasts genetically modified to express …

ED Schwartz, JS Shumsky, S Wehrli, A Tessler… - Experimental …, 2003 - Elsevier
The purpose of this study was to determine whether apparent diffusion coefficients (ADCs) in
ex vivo spinal cord white matter, calculated from diffusion weighted MR (DWI) images …

MRI diffusion coefficients in spinal cord correlate with axon morphometry

ED Schwartz, ET Cooper, Y Fan, AF Jawad, CL Chin… - …, 2005 - journals.lww.com
Following spinal cord injury, diffusion MRI (DWI) has been shown to detect injury and
functionally significant neuroprotection following treatment that otherwise would go …

Diffusion tensor imaging as a biomarker for assessing neuronal stem cell treatments affecting areas distal to the site of spinal cord injury

MB Jirjis, C Valdez, A Vedantam, BD Schmit… - … of Neurosurgery: Spine, 2017 - thejns.org
OBJECTIVE The aims of this study were to determine if the morphological and functional
changes induced by neural stem cell (NSC) grafts after transplantation into the rodent spinal …

[HTML][HTML] Feasibility of 3.0 T diffusion-weighted nuclear magnetic resonance imaging in the evaluation of functional recovery of rats with complete spinal cord injury

D Zhang, X Li, X Zhai, X He - Neural Regeneration Research, 2015 - journals.lww.com
Diffusion tensor imaging is a sensitive way to reflect axonal necrosis and degeneration, glial
cell regeneration and demyelination following spinal cord injury, and to display …

Numerical model for calculation of apparent diffusion coefficients (ADC) in permeable cylinders—comparison with measured ADC in spinal cord white matter

JC Ford, DB Hackney - Magnetic resonance in medicine, 1997 - Wiley Online Library
We have implemented a numerical method for calculation of the apparent diffusion
coefficient (ADC) in spinal cord injury, which takes into account the distribution of axon …

Ex vivo evaluation of ADC values within spinal cord white matter tracts

ED Schwartz, ET Cooper, CL Chin… - American journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Our purpose was to evaluate the effect of fixative on
apparent diffusion coefficient (ADC) values and anisotropy within spinal cord white matter …

MRI characterization of diffusion coefficients in a rat spinal cord injury model

JC Ford, DB Hackney, DC Alsop, H Jara… - Magnetic resonance …, 1994 - Wiley Online Library
Apparent diffusion coefficients (ADC) were measured in a rat spinal cord weight‐drop injury
model. After sacrifice, the spinal cords were fixed in situ and excised for MR imaging and …

Diffusion-weighted imaging of the spinal cord

ED Schwartz, CL Chin, M Takahashi… - Neuroimaging …, 2002 - neuroimaging.theclinics.com
Diffusion-weighted imaging (DWI) of the central nervous system can provide more
information concerning cell structure and integrity than conventional MR techniques. The …

DTI for assessing axonal integrity after contusive spinal cord injury and transplantation of oligodendrocyte progenitor cells

FA Bazley, A Pourmorteza, S Gupta… - … Conference of the …, 2012 - ieeexplore.ieee.org
We describe the feasibility of using diffusion tensor magnetic resonance imaging (DT-MRI)
to study a contusive model of rat spinal cord injury following human stem cell transplantation …