User profiles for Erik H. Middlebrooks
 | Erik MiddlebrooksProfessor & Consultant, Neuroradiology and Neurosurgery at Mayo Clinic Verified email at mayo.edu Cited by 3484 |
CNS small vessel disease: a clinical review
CNS small vessel disease (CSVD) causes 25% of strokes and contributes to 45% of dementia
cases. Prevalence increases with age, affecting about 5% of people aged 50 years to …
cases. Prevalence increases with age, affecting about 5% of people aged 50 years to …
A contemporary framework of language processing in the human brain in the context of preoperative and intraoperative language mapping
EH Middlebrooks, K Yagmurlu, JP Szaflarski… - Neuroradiology, 2017 - Springer
Introduction The emergence of advanced in vivo neuroimaging methods has redefined the
understanding of brain function with a shift from traditional localizationist models to more …
understanding of brain function with a shift from traditional localizationist models to more …
Differences in functional connectivity profiles as a predictor of response to anterior thalamic nucleus deep brain stimulation for epilepsy: a hypothesis for the …
EH Middlebrooks, SS Grewal, M Stead… - Neurosurgical …, 2018 - thejns.org
OBJECTIVE Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) is a
promising therapy for refractory epilepsy. Unfortunately, the variability in outcomes from ANT …
promising therapy for refractory epilepsy. Unfortunately, the variability in outcomes from ANT …
[HTML][HTML] Connectivity correlates to predict essential tremor deep brain stimulation outcome: evidence for a common treatment pathway
Background and purpose Deep brain stimulation (DBS) is the most common surgical treatment
for essential tremor (ET), yet there is variation in outcome and stimulation targets. This …
for essential tremor (ET), yet there is variation in outcome and stimulation targets. This …
[HTML][HTML] Structural connectivity–based segmentation of the thalamus and prediction of tremor improvement following thalamic deep brain stimulation of the ventral …
Objectives Traditional targeting methods for thalamic deep brain stimulation (DBS) performed
to address tremor have predominantly relied on indirect atlas-based methods that focus on …
to address tremor have predominantly relied on indirect atlas-based methods that focus on …
Functional activation patterns of deep brain stimulation of the anterior nucleus of the thalamus
EH Middlebrooks, C Lin, L Okromelidze, CQ Lu… - World Neurosurgery, 2020 - Elsevier
Background Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) is a
recently approved therapy for patients with drug-resistant epilepsy. To date, there is a poor …
recently approved therapy for patients with drug-resistant epilepsy. To date, there is a poor …
Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation
The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …
Acute brain activation patterns of high-versus low-frequency stimulation of the anterior nucleus of the thalamus during deep brain stimulation for epilepsy
BACKGROUND Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT)
is an increasingly utilized treatment of drug-resistant epilepsy. To date, the effect of high-…
is an increasingly utilized treatment of drug-resistant epilepsy. To date, the effect of high-…
Fiber tracts of the dorsal language stream in the human brain
OBJECT The aim of this study was to examine the arcuate (AF) and superior longitudinal
fasciculi (SLF), which together form the dorsal language stream, using fiber dissection and …
fasciculi (SLF), which together form the dorsal language stream, using fiber dissection and …
Segmentation of the globus pallidus internus using probabilistic diffusion tractography for deep brain stimulation targeting in Parkinson disease
BACKGROUND AND PURPOSE: Although globus pallidus internus deep brain stimulation
is a widely accepted treatment for Parkinson disease, there is persistent variability in …
is a widely accepted treatment for Parkinson disease, there is persistent variability in …
