Object. Primary meningiomas arising outside the intracranial compartment (primary extradural
meningiomas [PEMs]) are rare tumors. To develop a better understanding of these tumors …

OBJECTIVE: Two main forms of cell death are encountered in biology: apoptosis (ie,
programmed cell death) and necrosis (ie, accidental cell death). Because necrosis and apoptosis …

THIS REPORT, WITH an accompanying videotape, details the authors’ technique for performing
radical resections of tumors intrinsic to the insular lobe. The resection technique takes …

The records of 58 patients with gangliogliomas surgically treated between January 1, 1980,
and June 30, 1990, were retrospectively reviewed in order to determine long-term survival, …

Object. The extent of tumor resection that should be undertaken in patients with glioblastoma
multiforme (GBM) remains controversial. The purpose of this study was to identify …

Background It is unclear whether the benefit of adding whole-brain radiation therapy (WBRT)
to stereotactic radiosurgery (SRS) for the control of brain-tumours outweighs the potential …

The poor survival of patients with human malignant gliomas relates partly to the inability to
deliver therapeutic agents to the tumor. Because it has been suggested that circulating bone …

Despite extensive study, few therapeutic targets have been identified for glioblastoma (GBM).
Here we show that patient-derived glioma sphere cultures (GSCs) that resemble either the …

Background After brain metastasis resection, whole brain radiotherapy decreases local
recurrence, but might cause cognitive decline. We did this study to determine if stereotactic …

Purpose DNX-2401 (Delta-24-RGD; tasadenoturev) is a tumor-selective, replication-competent
oncolytic adenovirus. Preclinical studies demonstrated antiglioma efficacy, but the effects …