The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research
and clinical practice. Scientific advances in the past 7 years suggest that they might no …

Neuroaxonal damage is the pathological substrate of permanent disability in various
neurological disorders. Reliable quantification and longitudinal follow-up of such damage are …

The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016 Consortium of Multiple
Sclerosis Centres guidelines on the use of MRI in diagnosis and monitoring of multiple …

Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features
seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

Background and Purpose—MRI is more sensitive than CT for detection of age-related white
matter changes (ARWMC). Most rating scales estimate the degree and distribution of …

The type, frequency, and extent of MR signal abnormalities in Alzheimer's disease and normal
aging are a subject of controversy. With a 1.5-MR unit we studied 12 Alzheimer patients, …

… Fazekas F. Magnetic resonance signal abnormalities in asymptomatic individuals: their …
Pollay M, Curl F. Secrction of ccrebrospinal fluid by ventricular ependyma of the rabbit. Am J …

Background Under current guidelines, intravenous thrombolysis is used to treat acute stroke
only if it can be ascertained that the time since the onset of symptoms was less than 4.5 …

Background Glatiramer acetate, approved for the treatment of relapsing-remitting multiple
sclerosis, reduces relapses and disease activity and burden monitored by MRI. We assessed …

BACKGROUND AND PURPOSE: Patients with spontaneous intracerebral hemorrhage (ICH)
frequently have small areas of signal loss on gradient-echo T2*-weighted MR images, …