Identifying corticothalamic network epicenters in patients with idiopathic generalized epilepsy

GJ Ji, Z Zhang, Q Xu, Z Wang, J Wang… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Corticothalamic networks are considered core pathologic
substrates for idiopathic generalized epilepsy; however, the predominant epileptogenic …

[HTML][HTML] Large-scale cortico-subcortical functional networks in focal epilepsies: the role of the basal ganglia

E Výtvarová, R Mareček, J Fousek, O Strýček… - NeuroImage: Clinical, 2017 - Elsevier
Objectives The aim was to describe the contribution of basal ganglia (BG) thalamo-cortical
circuitry to the whole-brain functional connectivity in focal epilepsies. Methods Interictal …

Functional connectivity evidence of cortico–cortico inhibition in temporal lobe epilepsy

JI Tracy, K Osipowicz, P Spechler… - Human brain …, 2014 - Wiley Online Library
Epileptic seizures can initiate a neural circuit and lead to aberrant neural communication
with brain areas outside the epileptogenic region. We focus on interictal activity in focal …

Thalamo–cortical network pathology in idiopathic generalized epilepsy: insights from MRI-based morphometric correlation analysis

BC Bernhardt, DA Rozen, KJ Worsley, AC Evans… - Neuroimage, 2009 - Elsevier
Epileptic activity underlying idiopathic generalized epilepsy (IGE) is related to abnormal
thalamo–cortical interactions. Our purpose was to map in vivo the organization of the …

Altered thalamocortical functional connectivity in idiopathic generalized epilepsy

JB Kim, S Suh, WK Seo, K Oh, SB Koh, JH Kim - Epilepsia, 2014 - Wiley Online Library
Objective Aberrant thalamocortical network has been hypothesized to play a crucial role in
the fundamental pathogenesis underlying idiopathic generalized epilepsy (IGE). We aimed …

[HTML][HTML] Altered structural and functional thalamocortical networks in secondarily generalized extratemporal lobe seizures

SJ Peng, YL Hsin - NeuroImage: Clinical, 2017 - Elsevier
Structural and functional abnormalities in the thalamocortical network in primary generalized
epilepsies or mesial temporal lobe epilepsy have recently been identified by voxel-wise …

Probabilistic mapping of thalamic nuclei and thalamocortical functional connectivity in idiopathic generalised epilepsy

Y Chen, N Fallon, BAK Kreilkamp, C Denby… - Human brain …, 2021 - Wiley Online Library
It is well established that abnormal thalamocortical systems play an important role in the
generation and maintenance of primary generalised seizures. However, it is currently …

[HTML][HTML] Subcortical functional connectivity gradients in temporal lobe epilepsy

A Lucas, S Mouchtaris, EJ Cornblath, N Sinha… - NeuroImage: Clinical, 2023 - Elsevier
Abstract Background and Motivation Functional gradients have been used to study
differences in connectivity between healthy and diseased brain states, however this work …

[HTML][HTML] Pivotal role of subcortical structures as a network hub in focal epilepsy: evidence from graph theoretical analysis based on diffusion-tensor imaging

KM Park, BI Lee, KJ Shin, SY Ha, JS Park… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
Background and Purpose There is accumulating evidence that epilepsy is caused by
network dysfunction. We evaluated the hub reorganization of subcortical structures in …

Reduced thalamocortical functional connectivity in temporal lobe epilepsy

X He, GE Doucet, M Sperling, A Sharan, JI Tracy - Epilepsia, 2015 - Wiley Online Library
Objective In temporal lobe epilepsy (TLE), the thalamus is well known for its role in the
propagation and spread of epileptiform activity. However, the integrity of thalamocortical …