The purpose of this study was to evaluate quality parameters, metabolite concentrations and
concentration ratios, and to investigate the reproducibility of quantitative proton magnetic …

… trial of clinically isolated syndrome - Gijsbert JA Nagtegaal, Christoph Pohl, Mike P Wattjes,
… GJA Nagtegaal has received personal compensation for activities with Bayer Healthcare …

BACKGROUND AND PURPOSE: The considerable clinical effect of natalizumab in patients
with relapsing-remitting multiple sclerosis might be explained by its possible beneficial effect …

BACKGROUND AND PURPOSE: Natalizumab treatment strongly affects relapsing-remitting
multiple sclerosis, possibly by restraining white matter damage. This study investigated …

Purpose: Recent transcriptomic analyses have identified four distinct molecular subtypes of
colorectal cancer with evident clinical relevance. However, the requirement for sufficient …

Inshore massive corals often display bright luminescent lines that have been linked to river
flood plumes into coastal catchments and hence have the potential to provide a long-term …

Despite improved surgical treatment strategies for rectal cancer, 5–15% of all patients will
develop local recurrences. After conservative surgery, circumferential resection margin (CRM) …

Luminescent and geochemical properties of coral skeletons are increasingly used for time-series
analysis to resolve past and ongoing changes in environmental and climatic conditions…

Background Short-term preoperative radiotherapy and total mesorectal excision have each
been shown to improve local control of disease in patients with resectable rectal cancer. We …

PURPOSE: In retrospective studies, total mesorectal excision (TME) surgery has been
demonstrated to result in a reduction in the number of local recurrences of rectal cancer. Reports …