User profiles for H Moser

Heinz E. Moser

ETH, Caltech, Ciba-Geigy, Novartis, GeneSoft, Achaogen
Verified email at novartis.com
Cited by 7817

Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy.

HW Moser - Brain: a journal of neurology, 1997 - academic.oup.com
… irrespective of the baseline level or prior GTO therapy (HW Moser, unpublished observation).
See text for … in more than 100 patients (HW Moser, unpublished observation). Moderate …

[HTML][HTML] Towards the sustainable discovery and development of new antibiotics

…, L Fraisse, LJV Piddock, IH Gilbert, HE Moser… - Nature Reviews …, 2021 - nature.com
An ever-increasing demand for novel antimicrobials to treat life-threatening infections caused
by the global spread of multidrug-resistant bacterial pathogens stands in stark contrast to …

X-linked adrenoleukodystrophy

HW Moser, A Mahmood, GV Raymond - Nature Clinical Practice …, 2007 - nature.com
… Hugo W MoserMoser HW et al. (1982) The prenatal diagnosis of adrenoleukodystrophy.
Demonstration of increased hexacosanoic acid levels in cultured amniocytes and fetal adrenal …

Sequence-specific cleavage of double helical DNA by triple helix formation

HE Moser, PB Dervan - Science, 1987 - science.org
Homopyrimidine oligodeoxyribonucleotides with EDTA⋅Fe attached at a single position bind
the corresponding homopyrimidine-homopurine tracts within large double-stranded DNA …

The dynamics of bacterial populations maintained in the chemostat.

H Moser - The dynamics of bacterial populations maintained in …, 1958 - cabdirect.org
Under the controlled culture conditions in the chemostat, in nonsexual bacteria, the sole factors
influencing the genetic composition of the population are mutation and selection and this …

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

…, AM Douar, CO Sarde, P Kioschis, R Feil, H Moser… - Nature, 1993 - nature.com
ADRENOLEUKODYSTROPHY (ALD) is an X-linked disease affecting 1/20,000 males either
as cerebral ALD in childhood or as adrenomyeloneuropathy (AMN) in adults 1 . Childhood …

Adrenoleukodystrophy: increased plasma content of saturated very long chain fatty acids

HW Moser, AB Moser, KK Frayer, W Chen… - Neurology, 1998 - AAN Enterprises
With a new method we measured the saturated very long chain fatty acids in the plasma of
adrenoleukodystrophy (ALD) hemizygotes, ALD heterozygotes, and controls. ALD …

The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion

…, V Schneider, S Braga, H Moser… - American journal of …, 1989 - ncbi.nlm.nih.gov
About 60% of both Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD)
is due to deletions of the dystrophin gene. For cases with a deletion mutation, the “…

Antisense oligonucleotides

…, R Haener, P Martin, HE Moser - Accounts of Chemical …, 1995 - ACS Publications
Until a few decades ago, molecules that exert a therapeutic effect on the human body were
exclusively discovered byserendipity. As our understanding of molecular biology is …

ALEPH: a detector for electron-positron annihilations at LEP

…, JI Pascual, M Price, J Raguet, HG Moser… - Nucl. Instrum. Methods …, 1990 - cds.cern.ch
The design, construction, and performance of a large-mass 41r solid-angle detector with
solenoidal magnet is described. The detector serves to study electr0n—p0sitr0n annihilation …