Avidin–biotin system for delivery of diagnostic agents

H Sakahara, T Saga - Advanced drug delivery reviews, 1999 - Elsevier
… 3 h after … 36 h, 5 mg of avidin was injected, followed 24 h later by a third injection of 0.2 mg
of 99m Tc-biotin. Single photon emission computed tomography images were obtained 1–2 h

Expression of vascular endothelial growth factor (VEGF) in epithelial ovarian neoplasms: correlation with clinicopathology and patient survival, and analysis of serum …

…, H Kuroda, T Komatsu, K Nanbu, H Sakahara… - British journal of …, 1997 - nature.com
Vascular endothelial growth factor (VEGF) is known to be produced by various solid tumours
and is thought to be involved in microvascular permeability and/or angiogenesis. To …

Delayed 18F‐fluoro‐2‐deoxy‐D‐glucose positron emission tomography scan for differentiation between malignant and benign lesions in the pancreas

Y Nakamoto, T Higashi, H Sakahara, N Tamaki… - Cancer, 2000 - Wiley Online Library
… In malignant lesions, the SUV in 22 of 27 lesions increased at 2 hours (h) postinjection, and
the SUV also increased in 3 of 20 benign lesions. The retention index for malignant disease …

Specificity and affinity of 26 monoclonal antibodies against the CA 125 antigen: first report from the ISOBM TD-1 workshop

…, B Karlsson, FT Kreutz, D Jette, H Sakahara… - Tumor Biology, 1996 - karger.com
The specificity of 26 monoclonal antibodies against the CA 125 antigen was investigated in
two phases of the ISOBM TD-1 workshop. The binding specificity was studied using CA 125 …

18F-FDG PET in the detection of extrahepatic metastases from hepatocellular carcinoma

M Sugiyama, H Sakahara, T Torizuka, T Kanno… - Journal of …, 2004 - Springer
Background Positron emission tomography (PET) with 18 F-fluoro-2-deoxy-d-glucose ( 18 F-FDG)
is useful in detecting distant metastases from a variety of malignancies. However, its …

[PDF][PDF] FDG uptake, GLUT-1 glucose transporter and cellularity in human pancreatic tumors

…, T Torizuka, Y Nakamoto, H Sakahara… - Journal of Nuclear …, 1998 - Soc Nuclear Med
MATERIALS AND METhODS Patients The study group consisted of 36 patients with
suspected pancre atic tumors (18 men, 18 women; age range 19— 81 yr; mean age 60.9 yr) …

Comparison of hemodynamics of intracranial aneurysms between MR fluid dynamics using 3D cine phase-contrast MRI and MR-based computational fluid dynamics

…, MT Alley, R Bammer, NJ Pelc, H Namba, H Sakahara - Neuroradiology, 2010 - Springer
Introduction Hemodynamics is thought to play a very important role in the initiation, growth,
and rupture of intracranial aneurysms. The purpose of our study was to compare …

Diffusion-weighted echo planar imaging of ovarian tumors: is it useful to measure apparent diffusion coefficients?

…, T Ito, H Sakahara, A Nozaki, H Kabasawa - Journal of computer …, 2002 - journals.lww.com
Purpose Our goal was to test the hypothesis, as previously reported in other studies, that
apparent diffusion coefficients (ADCs) provide specific information to diagnose ovarian tumors, …

Clinical value of positron emission tomography with FDG for recurrent ovarian cancer

…, M Mandai, S Fujii, H Sakahara… - American Journal of …, 2001 - Am Roentgen Ray Soc
… Togashi, Toshihiro Higuchi, Masaki Mandai, Shingo Fujii, Harumi Sakahara, and Junji Konishi…
H and B identify physiologic uptakes in heart and bladder, respectively. … Harumi Sakahara

Avidin targeting of intraperitoneal tumor xenografts

Z Yao, M Zhang, H Sakahara, T Saga… - JNCI: Journal of the …, 1998 - academic.oup.com
Background: Lectins (proteins that bind specific sugar molecules on glycoproteins and
glycolipids) are expressed at various levels on the surface of tumor cells. Conjugation of cytotoxic …