The distortion of growth factor signalling is the most important prerequisite in tumour
progression. Transforming growth factor-β (TGFβ) signalling regulates tumour progression by a …

Trousseau's syndrome (cancer-associated thrombosis) is the second leading cause of death
in cancer patients, after death from cancer itself. The risk of a venous thromboembolism is 4…

The interferon-regulatory factor (IRF) family, originally identified as transcriptional regulators
of the type I interferon system, consists of nine members in mammals. A large number of …

Despite aggressive surgery, radiotherapy, and chemotherapy, treatment of malignant glioma
remains formidable. Although the concept of cancer stem cells reveals a new framework of …

To verify the hypothesis that the induction of a novel, efficient repair mechanism for chromosomal
DNA breaks may be involved in the radioadaptive response, the repair kinetics of DNA …

Although the concept of cancer stem cells or cancer-initiating cells had created a new paradigm
for the treatment of malignant tumors, it remains unclear how cancer-initiating cells can …

The E2A-HLF (hepatic leukemia factor) oncoprotein, generated in pro-B lymphocytes by fusion
of the trans-activation domain of E2A to the basic region/leucine zipper (bZIP) domain of …

Purpose: To retrospectively evaluate the effectiveness of fractionated stereotactic radiotherapy
(FSRT) for brain metastases from renal cell carcinoma (RCC). Methods and Materials: …

A nuclear magnetic resonance (NMR) study is reported for a 5 f-cooperative Jahn-Teller (JT)
system with antiferromagnetic ordering, UO 2, where we have performed magnetic actinide (…

Silica glass has excellent optical transparency, or very small optical loss, over a wide range
of wavelengths between the near infrared and the ultraviolet. Making intensive use of this …