Importance In multiple sclerosis (MS), chronic active lesions, which previously could only be
detected at autopsy, can now be identified on susceptibility-based magnetic resonance …

Objective: To determine the frequency and nature of leptomeningeal contrast enhancement
in multiple sclerosis (MS) via in vivo 3-tesla postcontrast T2-weighted, fluid-attenuated …

BACKGROUND. In some active multiple sclerosis (MS) lesions, a strong immune reaction at
the lesion edge may contain growth and thereby isolate the lesion from the surrounding …

Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the CNS
caused by the JC virus, which infects white and grey matter cells and leads to irreversible …

In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on
magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports …

Objective In multiple sclerosis (MS), accurate, in vivo characterization of dynamic inflammatory
pathological changes occurring in newly forming lesions could have major implications …

Objective: To assess the prevalence and the specificity of leptomeningeal enhancement (LME)
on postcontrast T2–fluid-attenuated inversion recovery (FLAIR) MRI in multiple sclerosis (…

The Genes and Environment in Multiple Sclerosis project establishes a platform to investigate
the events leading to multiple sclerosis (MS) in at‐risk individuals. It has recruited 2,632 …

Importance Subclinical inflammatory demyelination and neurodegeneration often precede
symptom onset in multiple sclerosis (MS). Objective To investigate the prevalence of brain …

Purpose of Review Progressive multifocal leukoencephalopathy (PML) is a severe opportunistic
infection that remains an important cause of morbidity and mortality in people living with …