The present and future of de novo whole-genome assembly
As the advent of next-generation sequencing (NGS) technology, various de novo assembly
algorithms based on the de Bruijn graph have been developed to construct chromosome-…
algorithms based on the de Bruijn graph have been developed to construct chromosome-…
A comprehensive review of hybrid forward osmosis systems: Performance, applications and future prospects
Forward osmosis (FO) has been increasingly studied in the past decade for its potential as
an emerging low-energy water and wastewater treatment process. However, the term “low-…
an emerging low-energy water and wastewater treatment process. However, the term “low-…
[HTML][HTML] Network of hypothalamic neurons that control appetite
JW Sohn - BMB reports, 2015 - ncbi.nlm.nih.gov
The central nervous system (CNS) controls food intake and energy expenditure via tight
coordinations between multiple neuronal populations. Specifically, two distinct neuronal …
coordinations between multiple neuronal populations. Specifically, two distinct neuronal …
[HTML][HTML] Trastuzumab deruxtecan in previously treated HER2-low advanced breast cancer
Background Among breast cancers without human epidermal growth factor receptor 2 (HER2)
amplification, overexpression, or both, a large proportion express low levels of HER2 that …
amplification, overexpression, or both, a large proportion express low levels of HER2 that …
[HTML][HTML] Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community
develops from a succession of key organisms. Disruption of the microbiota during maturation by …
develops from a succession of key organisms. Disruption of the microbiota during maturation by …
Second-order nonlinear-optical processes in orientationally ordered materials: relationship between molecular and macroscopic properties
… The indices I, J, and K define the coordinate system of the molecule, while indices i, j, and
k define those of the macroscopic material. The two coordinate systems are related by the …
k define those of the macroscopic material. The two coordinate systems are related by the …
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
AJ Schetter, SY Leung, JJ Sohn, KA Zanetti… - Jama, 2008 - jamanetwork.com
ContextMicroRNAs have potential as diagnostic biomarkers and therapeutic targets in
cancer. No study has evaluated the association between microRNA expression patterns and …
cancer. No study has evaluated the association between microRNA expression patterns and …
[HTML][HTML] Trastuzumab deruxtecan in previously treated HER2-positive breast cancer
…, H Iwata, Y Ito, J Tsurutani, J Sohn… - … England Journal of …, 2020 - Mass Medical Soc
Background Trastuzumab deruxtecan (DS-8201) is an antibody-drug conjugate composed
of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a cleavable …
of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a cleavable …
MONARCH 3: abemaciclib as initial therapy for advanced breast cancer
…, J Sohn, S Paluch-Shimon, J Huober… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Abemaciclib, a cyclin-dependent kinase 4 and 6 inhibitor, demonstrated efficacy as
monotherapy and in combination with fulvestrant in women with hormone receptor (HR)–…
monotherapy and in combination with fulvestrant in women with hormone receptor (HR)–…
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial
…, J Domont, LM Tseng, G Kunz, JH Sohn… - The Lancet, 2012 - thelancet.com
Background The anti-HER2 monoclonal antibody trastuzumab and the tyrosine kinase inhibitor
lapatinib have complementary mechanisms of action and synergistic antitumour activity …
lapatinib have complementary mechanisms of action and synergistic antitumour activity …
