The heterogeneity of plaque formation, the vascular remodelling response to plaque formation,
and the consequent phenotype of plaque instability attest to the extraordinarily complex …

Blood-flow-induced shear stress acting on the arterial wall is of paramount importance in
vascular biology. Endothelial cells sense shear stress and largely control its value in a feedback…

American Heart Association type IV plaques consist of a lipid core covered by a fibrous cap,
and develop at locations of eccentric low shear stress. Vascular remodeling initially …

Background—In-stent restenosis by excessive intimal hyperplasia reduces the long-term
clinical efficacy of coronary stents. Because shear stress (SS) is related to plaque growth in …

Mechanisms of in-stent restenosis are not fully understood. Shear stress is known to play a
role in plaque and thrombus formation and is sensitive to changes in regional vessel …

Background— Atherosclerosis preferentially develops at average low shear stress (SS)
locations. SS-related signaling maintains lumen dimensions by inducing outward arterial …

Objectives : The purpose of this study was to investigate the role of shear stress (SS) in
plaque regression. Background : A condition favorable to the development of atherosclerotic …

Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress). …

The role of shear stress in atherosclerosis has been well documented. However, its role in
restenosis was underexposed. In this paper a novel in vivo measuring technique and several …

… 12 Groen HC, Gijsen FJ, van der Lugt A, Ferguson MS, Hatsukami TS, van der Steen AF,
Yuan C, Wentzel JJ. Plaque rupture in the carotid artery is localized at the high shear stress …