Until recently, research on (S)-(-)-nicotine (1, hereafter simply nicotine) and nicotinic acetylcholine
receptors (nAChRs) emphasized two principal aspects. The first was the considerable …

The few days before and after birth are a time of special risk for stroke in both mother and
infant, probably related to activation of coagulation mechanisms in this critical period. Arterial …

Background— The aim of this study was to estimate the impact of thrombophilia on risk of first
childhood stroke through a meta-analysis of published observational studies. Methods and …

ContextNoncontrast computed tomography (CT) is the standard brain imaging study for the
initial evaluation of patients with acute stroke symptoms. Multimodal magnetic resonance …

The National Institute of Neurological Disorders and Stroke and the Office of Rare Disorders
sponsored a workshop on perinatal and childhood stroke in Bethesda, Maryland, on …

Ischemic perinatal stroke is a disorder associated with significant long-term neurologic morbidity.
With an estimated incidence of 1 in 2300 to 5000 births, stroke is more likely to occur in …

Perinatal stroke has become increasingly recognized, but the incidence is probably
underestimated because of variation in the presentation, evaluation, and diagnosis. Based on …

Background— The Women’s Health Initiative (WHI) Estrogen Alone trial assessed the balance
of benefits and risks of hormone use in healthy postmenopausal women. The trial was …

BACKGROUND: Neonatal arterial ischemic stroke (AIS) has emerged as a leading cause of
perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is poorly …

Stroke is an important cause of mortality and chronic morbidity in infants and children. Case
definitions for perinatal stroke have varied among studies by clinical and laboratory criteria. …