Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre …
…, A Panigrahy, Z Patay, B Tamrazi, JY Jones… - The lancet …, 2019 - thelancet.com
Background Paediatric low-grade glioma is the most common CNS tumour of childhood.
Although overall survival is good, disease often recurs. No single universally accepted …
Although overall survival is good, disease often recurs. No single universally accepted …
Imaging changes in pediatric intracranial ependymoma patients treated with proton beam radiation therapy compared to intensity modulated radiation therapy
…, M Chintagumpala, L Ketonen, JY Jones… - International Journal of …, 2015 - Elsevier
Purpose The clinical significance of magnetic resonance imaging (MRI) changes after
radiation therapy (RT) in children with ependymoma is not well defined. We compared imaging …
radiation therapy (RT) in children with ependymoma is not well defined. We compared imaging …
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study
…, G Vezina, C Bregman, Z Patay, JY Jones… - Neuro …, 2021 - academic.oup.com
Background Pediatric low-grade gliomas (pLGGs) are the most common childhood brain
tumor. Progression-free survival (PFS) is much lower than overall survival, emphasizing the …
tumor. Progression-free survival (PFS) is much lower than overall survival, emphasizing the …
Progression‐free survival of children with localized ependymoma treated with intensity‐modulated radiation therapy or proton‐beam radiation therapy
…, A Mahajan, E Jo, AC Paulino, AM Adesina, JY Jones… - Cancer, 2017 - Wiley Online Library
BACKGROUND The treatment for childhood intracranial ependymoma includes maximal
surgical resection followed by involved‐field radiotherapy, commonly in the form of intensity‐…
surgical resection followed by involved‐field radiotherapy, commonly in the form of intensity‐…
[HTML][HTML] Pediatric cerebral cavernous malformations: Genetics, pathogenesis, and management
…, VM Srinivasan, AC Mohan, JY Jones… - Surgical Neurology …, 2016 - ncbi.nlm.nih.gov
A 7‑year‑old girl presented with diplopia, ataxia, and headaches. Imaging revealed a
hemorrhagic right middle cerebellar peduncle lesion suggestive of a solitary CCM [Figure 2a]. Her …
hemorrhagic right middle cerebellar peduncle lesion suggestive of a solitary CCM [Figure 2a]. Her …
Severe neurologic side effects in patients being treated for hemophagocytic lymphohistiocytosis
Background Hemophagocytic Lymphohistiocytosis (HLH) is characterized by uncontrolled
inflammation that is generally fatal without immune modulating chemotherapy. At Texas …
inflammation that is generally fatal without immune modulating chemotherapy. At Texas …
Comparison of the diagnostic accuracy of PET/MRI to PET/CT-acquired FDG brain exams for seizure focus detection: a prospective study
MJ Paldino, E Yang, JY Jones, N Mahmood, A Sher… - Pediatric …, 2017 - Springer
Background There is great interest in positron emission tomography (PET)/magnetic resonance
(MR) as a clinical tool due to its capacity to provide diverse diagnostic information in a …
(MR) as a clinical tool due to its capacity to provide diverse diagnostic information in a …
Performance of computed tomography of the head to evaluate for skull fractures in infants with suspected non-accidental trauma
PA Culotta, JE Crowe, QA Tran, JY Jones… - Pediatric …, 2017 - Springer
Background Young children with suspected abusive head trauma often receive skull
radiographs to evaluate for fractures as well as computed tomography (CT) of the head to assess …
radiographs to evaluate for fractures as well as computed tomography (CT) of the head to assess …
Structure and dynamics of GPCRs in lipid membranes: physical principles and experimental approaches
Over the past decade, the vast amount of information generated through structural and
biophysical studies of GPCRs has provided unprecedented mechanistic insight into the complex …
biophysical studies of GPCRs has provided unprecedented mechanistic insight into the complex …
Increased risk of pseudoprogression among pediatric low-grade glioma patients treated with proton versus photon radiotherapy
Background Pseudoprogression (PsP) is a recognized phenomenon after radiotherapy (RT)
for high-grade glioma but is poorly characterized for low-grade glioma (LGG). We sought to …
for high-grade glioma but is poorly characterized for low-grade glioma (LGG). We sought to …