Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations
Bone marrow stromal cells (MSC) are non-hematopoietic support cells that can be easily
derived from bone marrow aspirates. Human MSC are clinically attractive because they can be …
derived from bone marrow aspirates. Human MSC are clinically attractive because they can be …
Recovery of function following grafting of human bone marrow-derived stromal cells into the injured spinal cord
…, GC Kopen, J Wagner, JS Shumsky… - … and neural repair, 2006 - journals.sagepub.com
This study evaluates functional recovery after transplanting human bone marrow-derived
stromal cells (BMSCs) into contusion models of spinal cord injury (SCI). The authors used a …
stromal cells (BMSCs) into contusion models of spinal cord injury (SCI). The authors used a …
Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and …
Transplanting neuronal and glial restricted precursors (NRP/GRP) into a midthoracic injury
9 d after contusion improved bladder and motor function, diminished thermal hypersensitivity, …
9 d after contusion improved bladder and motor function, diminished thermal hypersensitivity, …
Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation
…, SA Swanger, V Madhvani, JS Shumsky… - Journal of …, 2006 - liebertpub.com
Cell transplantation as a treatment for spinal cord injury is a promising therapeutic strategy
whose effective clinical application would be facilitated by non-invasive delivery protocols. …
whose effective clinical application would be facilitated by non-invasive delivery protocols. …
Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression
CA Tobias, SSW Han, JS Shumsky, D Kim… - Journal of …, 2005 - liebertpub.com
Encapsulation of cells has the potential to provide a protective barrier against host immune
cell interactions after grafting. Previously we have shown that alginate encapsulated BDNF-…
cell interactions after grafting. Previously we have shown that alginate encapsulated BDNF-…
Differential sensitivity to psychostimulants across prefrontal cognitive tasks: differential involvement of noradrenergic α1-and α2-receptors
CW Berridge, JS Shumsky, ME Andrzejewski… - Biological …, 2012 - Elsevier
BACKGROUND: Psychostimulants improve a variety of cognitive and behavioral processes
in patients with attention-deficit/hyperactivity disorder (ADHD). Limited observations suggest …
in patients with attention-deficit/hyperactivity disorder (ADHD). Limited observations suggest …
Forced exercise as a rehabilitation strategy after unilateral cervical spinal cord contusion injury
HR Sandrow-Feinberg, J Izzi, JS Shumsky… - Journal of …, 2009 - liebertpub.com
Abstract Evaluation of locomotor training after spinal cord injury (SCI) has primarily focused
on hind limb recovery, with evidence of functional and molecular changes in response to …
on hind limb recovery, with evidence of functional and molecular changes in response to …
Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats
We examined whether fibroblasts, genetically modified to express BDNF and NT-3 (Fb-BDNF/NT3)
and transplanted into a thoracic spinal injury site, would enhance recovery of bladder …
and transplanted into a thoracic spinal injury site, would enhance recovery of bladder …
[HTML][HTML] Group II metabotropic glutamate receptor agonist ameliorates MK801-induced dysfunction of NMDA receptors via the Akt/GSK-3β pathway in adult rat …
…, RY Gao, AE Adelman, W Zhang, JS Shumsky… - …, 2011 - nature.com
Pharmacological intervention targeting mGluRs has emerged as a potential treatment for
schizophrenia, whereas the mechanisms involved remain elusive. We explored the …
schizophrenia, whereas the mechanisms involved remain elusive. We explored the …
Apparent diffusion coefficients in spinal cord transplants and surrounding white matter correlate with degree of axonal dieback after injury in rats
ED Schwartz, CL Chin, JS Shumsky… - American journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Abnormal apparent diffusion coefficient (ADC) values in
injured spinal cord white matter and fibroblast transplants have been shown to correspond …
injured spinal cord white matter and fibroblast transplants have been shown to correspond …
