Diffusion/perfusion MR imaging of acute cerebral ischemia

J Kucharczyk, J Mintorovitch, HS Asgari… - Magnetic resonance …, 1991 - Wiley Online Library
In vivo echo‐planar MR imaging was used to measure apparent diffusion coefficients (ADC)
of cerebral tissues in a comprehensive noninvasive evaluation of early ischemic brain …

Identification of “premyelination” by diffusion-weighted MRI

…, LM Prayer, ME Moseley, J Kucharczyk - Journal of computer …, 1995 - journals.lww.com
Objective The purpose of this study was to compare white matter maturation as demonstrated
with diffusion-weighted MRI and with myelin-sensitive histological staining. Materials and …

Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass

…, L Meoli, E Nestoridi, NK Gupta, S Kvas, J Kucharczyk… - Science, 2013 - science.org
The resolution of type 2 diabetes after Roux-en-Y gastric bypass (RYGB) attests to the
important role of the gastrointestinal tract in glucose homeostasis. Previous studies in RYGB-…

Echo-planar perfusion-sensitive MR imaging of acute cerebral ischemia.

J Kucharczyk, ZS Vexler, TP Roberts, HS Asgari… - Radiology, 1993 - pubs.rsna.org
T2*-sensitive echo-planar magnetic resonance imaging was used with first-pass magnetic
susceptibility contrast enhancement in a cat model of acute regional stroke to evaluate the …

Anisotropy in diffusion‐weighted MRI

ME Moseley, J Kucharczyk, HS Asgari… - Magnetic Resonance …, 1991 - Wiley Online Library
Diffusional anisotropy of water protons, induced by nonrandom, directional barriers which
hinder or retard water motion, is measurable by MRI. Faster water diffusion was observed …

Diffusion-Weighted Magnetic Resonance Imaging of Acute Focal Cerebral Ischemia: Comparison of Signal Intensity with Changes in Brain Water and Na+,K+ …

…, GY Yang, H Shimizu, J Kucharczyk… - Journal of Cerebral …, 1994 - journals.sagepub.com
Diffusion-weighted magnetic resonance (MR) images from rats during acute cerebral
ischemia induced by middle cerebral artery occlusion were analyzed for correspondence with …

MR imaging of the brain in patients with diabetes insipidus.

…, J Kucharczyk, W Kucharczyk - American journal of …, 1991 - Am Soc Neuroradiology
Diabetes insipidus is a clinical syndrome characterized by the excretion of copious volumes
of dilute urine combined with persistent intake of abnormally large quantities of fluid. There …

The effect of phospholipid vesicles on the NMR relaxation of water: an explanation for the MR appearance of the neurohypophysis?

W Kucharczyk, RE Lenkinski… - American Journal …, 1990 - Am Soc Neuroradiology
The normal neurohypophysis is hyperintense relative to brain and adenohypophysis on T1-weighted
MR images, but the signal is not chemically shifted with respect to water. The …

Targeting toll-like receptors for cancer therapy

MJ Braunstein, J Kucharczyk, S Adams - Targeted oncology, 2018 - Springer
The immune system encompasses a broad array of defense mechanisms against foreign
threats, including invading pathogens and transformed neoplastic cells. Toll-like receptors (…

Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice

E Nestoridi, S Kvas, J Kucharczyk… - Endocrinology, 2012 - academic.oup.com
Although the prevalence of obesity has increased dramatically throughout the world during
the last 25 yr, its long-term control remains poor. Currently, only gastrointestinal weight loss …