62Cu-diacetyl-bis (N4-methylthiosemicarbazone) PET in human gliomas: comparative study with [18F] fluorodeoxyglucose and L-methyl-[11C] methionine PET

K Tateishi, U Tateishi, S Nakanowatari… - American Journal …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) was
developed as a hypoxic radiotracer in PET. We compared imaging features among MR …

Prognostic implications of 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) PET/CT in patients with glioma

A Toriihara, M Ohtake, K Tateishi… - Annals of nuclear …, 2018 - Springer
Objective The potential of positron emission tomography/computed tomography using 62 Cu-
diacetyl-bis (N 4-methylthiosemicarbazone)(62 Cu-ATSM PET/CT), which was originally …

Application of 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) PET imaging to predict highly malignant tumor grades and hypoxia-inducible factor-1α expression in …

K Tateishi, U Tateishi, M Sato… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Hypoxic tissue evaluation in glioma is important for
predicting treatment response and establishing antihypoxia therapy. In this preliminary …

Substitution of 11C-methionine PET by perfusion MRI during the follow-up of treated high-grade gliomas: preliminary results in clinical practice

V Dandois, D Rommel, L Renard, J Jamart… - Journal of …, 2010 - Elsevier
PURPOSE: Our aim was to compare perfusion magnetic resonance imaging (MRI) and
positron emission tomography (PET) using carbon-11 labelled methionine (MET) in gliomas …

Tumor hypoxia and microscopic diffusion capacity in brain tumors: A comparison of 62Cu-Diacetyl-Bis (N4-Methylthiosemicarbazone) PET/CT and diffusion-weighted …

A Hino-Shishikura, U Tateishi, H Shibata… - European journal of …, 2014 - Springer
Objectives The aim of this study was to clarify the relationship between tumor hypoxia and
microscopic diffusion capacity in primary brain tumors using 62 Cu-Diacetyl-Bis (N4 …

11C-methionine PET for grading and prognostication in gliomas: a comparison study with 18F-FDG PET and contrast enhancement on MRI

T Singhal, TK Narayanan, MP Jacobs… - Journal of Nuclear …, 2012 - Soc Nuclear Med
The aim of this study was to compare the grading and prognostic value of l-[methyl-11C]-
methionine (11C-MET) PET in glioma patients with 18F-FDG PET and contrast-enhanced …

Diagnostic and prognostic value of 11C-methionine PET for nonenhancing gliomas

K Takano, M Kinoshita, H Arita… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Noninvasive radiologic evaluation of glioma can facilitate
correct diagnosis and detection of malignant transformation. Although positron-emission …

Comparison of 4′-[methyl-11C]thiothymidine (11C-4DST) and 3′-deoxy-3′-[18F]fluorothymidine (18F-FLT) PET/CT in human brain glioma imaging

Y Toyota, K Miyake, N Kawai, T Hatakeyama… - EJNMMI research, 2015 - Springer
Abstract Background 3′-deoxy-3′-[18 F] fluorothymidine (18 F-FLT) has been used to
evaluate tumor malignancy and cell proliferation in human brain gliomas. However, 18 F …

Hypoxia PET imaging beyond 18F-FMISO in patients with high-grade glioma: 18F-FAZA and other hypoxia radiotracers

N Quartuccio, R Laudicella, P Mapelli… - Clinical and …, 2020 - Springer
Purpose High-grade gliomas are aggressive primitive brain tumors presenting aberrant
vasculature, regional necrosis, and areas of hypoxia. Tumor hypoxia is associated with …

Imaging of hypoxic lesions in patients with gliomas by using positron emission tomography with 1-(2-[18F] fluoro-1-[hydroxymethyl] ethoxy) methyl-2-nitroimidazole, a …

I Shibahara, T Kumabe, M Kanamori, R Saito… - Journal of …, 2010 - thejns.org
Object Assessment of hypoxic conditions in brain tumors is important for predicting tumor
aggressiveness and treatment response. A new hypoxia imaging agent, 1-(2-[18 F] fluoro-1 …