User profiles for K.K. Tha
Khin Khin ThaFaculty of Medicine, Hokkaido University Verified email at med.hokudai.ac.jp Cited by 2512 |
[HTML][HTML] Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment
Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent
diseases ranging from cancer and Alzheimer’s disease to COVID-19 with significant clinical …
diseases ranging from cancer and Alzheimer’s disease to COVID-19 with significant clinical …
Changes in expressions of proinflammatory cytokines IL-1β, TNF-α and IL-6 in the brain of senescence accelerated mouse (SAM) P8
KK Tha, Y Okuma, H Miyazaki, T Murayama, T Uehara… - Brain research, 2000 - Elsevier
The senescence-accelerated mouse (SAM) is known to be a murine model for accelerated
aging. The SAMP8 strain shows age-related deterioration of learning and memory at an …
aging. The SAMP8 strain shows age-related deterioration of learning and memory at an …
[HTML][HTML] Identifying triple-negative breast cancer using background parenchymal enhancement heterogeneity on dynamic contrast-enhanced MRI: a pilot radiomics …
Objectives To determine the added discriminative value of detailed quantitative characterization
of background parenchymal enhancement in addition to the tumor itself on dynamic …
of background parenchymal enhancement in addition to the tumor itself on dynamic …
Prognostic imaging biomarkers in glioblastoma: development and independent validation on the basis of multiregion and quantitative analysis of MR images
… KK Activities related to the present article: disclosed no relevant activities. Activities not related
to the present article: JSPS KAKENHI grant in aid for scientific research and personal fees …
to the present article: JSPS KAKENHI grant in aid for scientific research and personal fees …
Noninvasive electrical conductivity measurement by MRI: a test of its validity and the electrical conductivity characteristics of glioma
KK Tha, U Katscher, S Yamaguchi, C Stehning… - European …, 2018 - Springer
Objectives This study noninvasively examined the electrical conductivity (σ) characteristics
of diffuse gliomas using MRI and tested its validity. Methods MRI including a 3D steady-state …
of diffuse gliomas using MRI and tested its validity. Methods MRI including a 3D steady-state …
Radiomics and radiogenomics for precision radiotherapy
Imaging plays an important role in the diagnosis and staging of cancer, as well as in radiation
treatment planning and evaluation of therapeutic response. Recently, there has been …
treatment planning and evaluation of therapeutic response. Recently, there has been …
Chronic ischemia alters brain microstructural integrity and cognitive performance in adult moyamoya disease
K Kazumata, KK Tha, H Narita, I Kusumi, H Shichinohe… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— The mechanisms underlying frontal lobe dysfunction in moyamoya
disease (MMD) are unknown. We aimed to determine whether chronic ischemia induces …
disease (MMD) are unknown. We aimed to determine whether chronic ischemia induces …
[HTML][HTML] Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for …
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using
the current diagnostic system based on presenting symptoms and signs. The creation of a …
the current diagnostic system based on presenting symptoms and signs. The creation of a …
Intravoxel incoherent motion diffusion-weighted imaging in head and neck squamous cell carcinoma: assessment of perfusion-related parameters compared to …
…, T Sakashita, A Homma, A Tsukahara, KK Tha… - Magnetic resonance …, 2014 - Elsevier
Purpose To investigate the correlation between perfusion-related parameters obtained with
intravoxel incoherent motion (IVIM) and classical perfusion parameters obtained with …
intravoxel incoherent motion (IVIM) and classical perfusion parameters obtained with …
[HTML][HTML] Therapeutic potency of nanoformulations of siRNAs and shRNAs in animal models of cancers
RNA Interference (RNAi) has brought revolutionary transformations in cancer management
in the past two decades. RNAi-based therapeutics including siRNA and shRNA have …
in the past two decades. RNAi-based therapeutics including siRNA and shRNA have …