User profiles for K.K. Tha

Khin Khin Tha

Faculty of Medicine, Hokkaido University
Verified email at med.hokudai.ac.jp
Cited by 2512

[HTML][HTML] Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment

…, ST Haque, H Al-Busaidi, A Bakhtiar, KK Tha… - Archives of pharmacal …, 2022 - Springer
Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent
diseases ranging from cancer and Alzheimer’s disease to COVID-19 with significant clinical …

Changes in expressions of proinflammatory cytokines IL-1β, TNF-α and IL-6 in the brain of senescence accelerated mouse (SAM) P8

KK Tha, Y Okuma, H Miyazaki, T Murayama, T Uehara… - Brain research, 2000 - Elsevier
The senescence-accelerated mouse (SAM) is known to be a murine model for accelerated
aging. The SAMP8 strain shows age-related deterioration of learning and memory at an …

[HTML][HTML] Identifying triple-negative breast cancer using background parenchymal enhancement heterogeneity on dynamic contrast-enhanced MRI: a pilot radiomics …

…, F Kato, N Oyama-Manabe, R Li, Y Cui, KK Tha… - PloS one, 2015 - journals.plos.org
Objectives To determine the added discriminative value of detailed quantitative characterization
of background parenchymal enhancement in addition to the tumor itself on dynamic …

Prognostic imaging biomarkers in glioblastoma: development and independent validation on the basis of multiregion and quantitative analysis of MR images

Y Cui, KK Tha, S Terasaka, S Yamaguchi, J Wang… - Radiology, 2016 - pubs.rsna.org
KK Activities related to the present article: disclosed no relevant activities. Activities not related
to the present article: JSPS KAKENHI grant in aid for scientific research and personal fees …

Noninvasive electrical conductivity measurement by MRI: a test of its validity and the electrical conductivity characteristics of glioma

KK Tha, U Katscher, S Yamaguchi, C Stehning… - European …, 2018 - Springer
Objectives This study noninvasively examined the electrical conductivity (σ) characteristics
of diffuse gliomas using MRI and tested its validity. Methods MRI including a 3D steady-state …

Radiomics and radiogenomics for precision radiotherapy

J Wu, KK Tha, L Xing, R Li - Journal of radiation research, 2018 - academic.oup.com
Imaging plays an important role in the diagnosis and staging of cancer, as well as in radiation
treatment planning and evaluation of therapeutic response. Recently, there has been …

Chronic ischemia alters brain microstructural integrity and cognitive performance in adult moyamoya disease

K Kazumata, KK Tha, H Narita, I Kusumi, H Shichinohe… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— The mechanisms underlying frontal lobe dysfunction in moyamoya
disease (MMD) are unknown. We aimed to determine whether chronic ischemia induces …

[HTML][HTML] Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for …

…, T Itahashi, M Nakataki, R Hashimoto, KK Tha… - Molecular …, 2023 - nature.com
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using
the current diagnostic system based on presenting symptoms and signs. The creation of a …

Intravoxel incoherent motion diffusion-weighted imaging in head and neck squamous cell carcinoma: assessment of perfusion-related parameters compared to …

…, T Sakashita, A Homma, A Tsukahara, KK Tha… - Magnetic resonance …, 2014 - Elsevier
Purpose To investigate the correlation between perfusion-related parameters obtained with
intravoxel incoherent motion (IVIM) and classical perfusion parameters obtained with …

[HTML][HTML] Therapeutic potency of nanoformulations of siRNAs and shRNAs in animal models of cancers

ME Karim, KK Tha, I Othman, M Borhan Uddin… - Pharmaceutics, 2018 - mdpi.com
RNA Interference (RNAi) has brought revolutionary transformations in cancer management
in the past two decades. RNAi-based therapeutics including siRNA and shRNA have …