Moving toward a consensus DSC-MRI protocol: validation of a low–flip angle single-dose option as a reference standard for brain tumors
KM Schmainda, MA Prah, LS Hu… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: DSC-MR imaging using preload, intermediate (60°) flip
angle and postprocessing leakage correction has gained traction as a standard …
angle and postprocessing leakage correction has gained traction as a standard …
The effect of pulse sequence parameters and contrast agent dose on percentage signal recovery in DSC-MRI: implications for clinical applications
JL Boxerman, ES Paulson, MA Prah… - American Journal of …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Both technical and pathophysiologic factors affect PSR in
DSC-MR imaging. We aimed to determine how TE, flip angle (α), and contrast dose impact …
DSC-MR imaging. We aimed to determine how TE, flip angle (α), and contrast dose impact …
Utility of percentage signal recovery and baseline signal in DSC-MRI optimized for relative CBV measurement for differentiating glioblastoma, lymphoma, metastasis …
BACKGROUND AND PURPOSE: The percentage signal recovery in non-leakage-corrected
(no preload, high flip angle, intermediate TE) DSC-MR imaging is known to differ …
(no preload, high flip angle, intermediate TE) DSC-MR imaging is known to differ …
Optimization of DSC MRI echo times for CBV measurements using error analysis in a pilot study of high-grade gliomas
BACKGROUND AND PURPOSE: The optimal TE must be calculated to minimize the
variance in CBV measurements made with DSC MR imaging. Simulations can be used to …
variance in CBV measurements made with DSC MR imaging. Simulations can be used to …
Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials
BM Ellingson, M Bendszus, J Boxerman… - Neuro …, 2015 - academic.oup.com
A recent joint meeting was held on January 30, 2014, with the US Food and Drug
Administration (FDA), National Cancer Institute (NCI), clinical scientists, imaging experts …
Administration (FDA), National Cancer Institute (NCI), clinical scientists, imaging experts …
Multisite concordance of DSC-MRI analysis for brain tumors: results of a national cancer institute quantitative imaging network collaborative project
KM Schmainda, MA Prah, SD Rand… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Standard assessment criteria for brain tumors that only
include anatomic imaging continue to be insufficient. While numerous studies have …
include anatomic imaging continue to be insufficient. While numerous studies have …
Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas
Despite the widespread clinical use of dynamic susceptibility contrast (DSC) MRI, DSC-MRI
methodology has not been standardized, hindering its utilization for response assessment in …
methodology has not been standardized, hindering its utilization for response assessment in …
Optimization of acquisition and analysis methods for clinical dynamic susceptibility contrast MRI using a population-based digital reference object
BACKGROUND AND PURPOSE: The accuracy of DSC-MR imaging CBV maps in
glioblastoma depends on acquisition and analysis protocols. Multisite protocol …
glioblastoma depends on acquisition and analysis protocols. Multisite protocol …
Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients
AM Stokes, M Bergamino, L Alhilali… - Journal of Cerebral …, 2021 - journals.sagepub.com
Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC)
MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we …
MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we …
Systematic assessment of multi‐echo dynamic susceptibility contrast MRI using a digital reference object
AM Stokes, NB Semmineh… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Brain tumor dynamic susceptibility contrast (DSC) MRI is adversely impacted by T1
and contrast agent leakage effects that result in inaccurate hemodynamic metrics. While …
and contrast agent leakage effects that result in inaccurate hemodynamic metrics. While …
