Like asthma and atopic dermatitis, allergic rhinitis is an allergic disease, but of the three, it is
the only type I allergic disease. Allergic rhinitis includes pollinosis, which is intractable and …

Background The SQ house dust mite ( HDM ) sublingual immunotherapy ( SLIT )‐tablet ( TO
‐203, Torii, Japan/ ALK , Denmark) treatment has been effective against respiratory allergic …

ESRP1 (epithelial splicing regulatory protein 1) and ESRP2 regulate alternative splicing
events associated with epithelial phenotypes of cells, and both are down-regulated during the …

Evidence has accumulated indicating that only a minority of cancer cells with stem cell
properties, cancer stem cells (CSCs), are responsible for maintenance and growth of the tumor. …

Background CD44 was found as a surface marker in cancer stem cell (CSC) of squamous
cell carcinoma of the head and neck (SCCHN); however, the immunologic properties of such …

Myeloid‐derived suppressor cells ( MDSC ) represent a heterogeneous population and have
the potential to suppress immune responses via diverse mechanisms. In recent studies, a …

Background The SQ house dust mite (HDM) sublingual immunotherapy (SLIT) tablet has been
approved in 11 European countries and Japan for patients with HDM-induced respiratory …

Epithelial cell‐derived thymic stromal lymphopoietin (TSLP) is a master switch for asthma or
atopic dermatitis by inducing a dendritic cell‐mediated Th2‐type allergic inflammation. …

We have studied the expression of the gene encoding the ε heavy chain of IgE in nasal B
cells of hayfever patients. We developed probes to detect transcripts of the ε germ‐line gene …

Background The efficacy and safety of 300 index of reactivity (IR) tablets of house dust mite (HDM)
allergen extracts in Japanese pediatric (5‐16 years old) patients with allergic rhinitis (…