Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose–response framework

…, T Lettieri, SZ Liu, A Maisseu, KI Maynard… - Toxicology and applied …, 2007 - Elsevier
Many biological subdisciplines that regularly assess dose–response relationships have
identified an evolutionarily conserved process in which a low dose of a stressful stimulus …

Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries

K Nozaki, MA Moskowitz, KI Maynard… - Journal of cerebral …, 1993 - journals.sagepub.com
The distribution of perivascular nerve fibers expressing nitric oxide synthase (NOS)-immunoreactivity
was examined in Sprague–Dawley and Long–Evans rats using affinity-purified …

Delayed Treatment With Nicotinamide (Vitamin B3) Improves Neurological Outcome and Reduces Infarct Volume After Transient Focal Cerebral Ischemia in Wistar …

…, Y Sakakibara, EJ Lee, CS Ogilvy, KI Maynard - Stroke, 2000 - Am Heart Assoc
Background and Purpose—We have previously shown that nicotinamide (NAm) acutely
reduces brain infarction induced by permanent middle cerebral artery occlusion (MCAo) in rats. …

Acute administration of Ginkgo biloba extract (EGb 761) affords neuroprotection against permanent and transient focal cerebral ischemia in Sprague‐Dawley rats

…, TS Wu, TY Chen, IA Ayoub, KI Maynard - Journal of …, 2002 - Wiley Online Library
We examined the neuroprotective action of a standardized extract of Ginkgo biloba leaves (EGb
761) in permanent and transient middle cerebral artery (MCA) occlusion models in …

Prevention of nitric oxide-induced neuronal injury through the modulation of independent pathways of programmed cell death

…, A Vincent, T Shaw, KI Maynard… - Journal of Cerebral …, 2000 - journals.sagepub.com
Neuronal injury may be dependent upon the generation of the free radical nitric oxide (NO)
and the subsequent induction of programed cell death (PCD). Although the nature of this …

Nicotinamide reduces infarction up to two hours after the onset of permanent focal cerebral ischemia in Wistar rats

IA Ayoub, EJ Lee, CS Ogilvy, MF Beal, KI Maynard - Neuroscience letters, 1999 - Elsevier
Ischemia depletes ATP and initiates cascades leading to irreversible tissue injury. Nicotinamide
is a precursor of nicotinamide adenine dinucleotide (NAD + ) which increases neuronal …

Compensation for encoder geometry and shaft speed variation in time interval torsional vibration measurement

BR Resor, MW Trethewey, KP Maynard - Journal of sound and vibration, 2005 - Elsevier
Digital time interval techniques for the measurement of torsional vibrations in rotating shafts
have been used in a variety of applications. The techniques use high-speed timers to detect …

Nitric oxide produced during ischemia improves functional recovery in the rabbit retina

KI Maynard, D Chen, PM Arango, CS Ogilvy - Neuroreport, 1996 - journals.lww.com
We examined the effect of modulating endogenous nitric oxide (NO) production on the recovery
of neuronal function from temporary ischemia using a preparation in which blood flow is …

Post-treatment with nicotinamide (vitamin B3) reduces the infarct volume following permanent focal cerebral ischemia in female Sprague–Dawley and Wistar rats

Y Sakakibara, AP Mitha, CS Ogilvy, KI Maynard - Neuroscience letters, 2000 - Elsevier
Delayed treatment with nicotinamide (NAm) protects male rats against cerebral ischemia.
Since the preponderant use of male animals in stroke research may produce results not …

Selective 5-HT1D alpha serotonin receptor gene expression in trigeminal ganglia: implications for antimigraine drug development.

GW Rebeck, KI Maynard, BT Hyman… - Proceedings of the …, 1994 - National Acad Sciences
Pharmacological data suggest that the actions of antimigraine drugs such as sumatriptan may
be mediated by 5-HT1D-like serotonin receptors on trigeminovascular nerve endings. We …