Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients

…, T Suzuki, T Ohkubo, K Sugawara, K Otani - Progress in Neuro …, 2002 - Elsevier
The presence of the long (l) variant of the serotonin (5-hydroxytryptamine: 5-HT) transporter
gene-linked polymorphic region (5-HTTLPR) is reported to be associated with a more …

Is the predisposition to neuroleptic malignant syndrome genetically transmitted?

K Otani, M Horiuchi, T Kondo, S Kaneko… - The British Journal of …, 1991 - cambridge.org
Discussion The clinical symptoms of the present cases fulfilled the criteria for NMS proposed
by Pope et a!(1986). In case one, the causal relationship between the episodes and the …

Teratogenicity of antiepileptic drugs: analysis of possible risk factors

S Kaneko, K Otani, Y Fukushima, Y Ogawa… - …, 1988 - Wiley Online Library
: To determine the primary factors responsible for the increased incidence of malformation
in the offspring of antiepileptic drug (AED)‐treated epileptic mothers, special attention was …

Associated factors of rehospitalization among schizophrenic patients

…, S Yasumura, A Fukao, K Otani - Psychiatry and Clinical …, 2003 - Wiley Online Library
The purpose of the present study was to identify the associated factors of rehospitalization
in schizophrenic patients. A case‐control study was conducted. The cases consisted of …

A three‐factor model of the MADRS in major depressive disorder

…, K Yoshida, H Higuchi, T Shimizu, K Otani - Depression and …, 2005 - Wiley Online Library
Major Depressive Disorder (MDD) may be composed of some symptom clusters with distinct
neurochemical disturbances, suggesting the importance of the factor analysis of depressive …

Parental overprotection increases interpersonal sensitivity in healthy subjects

K Otani, A Suzuki, Y Matsumoto, M Kamata - Comprehensive Psychiatry, 2009 - Elsevier
The effect of parental rearing on interpersonal sensitivity was studied in 469 Japanese
volunteers. Perceived parental rearing was assessed by the Parental Bonding Instrument, which …

The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake …

…, A Ikenouchi-Sugita, H Hori, K Otani… - Progress in Neuro …, 2011 - Elsevier
BACKGROUND: We investigated the relationship between a brain-derived neurotrophic
factor (BDNF) polymorphism (Val66Met) and the clinical response of patients with major …

Monoamine oxidase: a gene polymorphism, tryptophan hydroxylase gene polymorphism and antidepressant response to fluvoxamine in Japanese patients with major …

…, T Suzuki, T Ohkubo, K Sugawara, K Otani - Progress in Neuro …, 2002 - Elsevier
Monoamine oxidase A (MAOA) and tryptophan hydroxylase (TPH) are the staple enzymes
in the metabolism of serotonin (5-HT). The genetic polymorphisms of these two enzymes …

Correlations of interpersonal sensitivity with negative working models of the self and other: evidence for link with attachment insecurity

K Otani, A Suzuki, Y Matsumoto, N Shibuya… - Annals of general …, 2014 - Springer
Background It has been suggested that interpersonal sensitivity, a personality trait associated
with depression and anxiety disorders, is linked with attachment insecurity. To confirm this …

Influences of parental rearing on the personality traits of healthy Japanese

S Oshino, A Suzuki, G Ishii, K Otani - Comprehensive Psychiatry, 2007 - Elsevier
Influences of parental rearing on the personality traits of healthy subjects were studied in
323 Japanese volunteers. Perceived parental rearing was assessed with the use of the …