Neuropsychological outcomes of several storage diseases with and without bone marrow transplantation
EG Shapiro, LA Lockman, M Balthazor… - Journal of inherited …, 1995 - Springer
Neuropsychological assessment is essential in providing documentation of the untreated
natural history of storage diseases associated with dementia and quantifying the effectiveness …
natural history of storage diseases associated with dementia and quantifying the effectiveness …
Microglia: the effector cell for reconstitution of the central nervous system following bone marrow transplantation for lysosomal and peroxisomal storage diseases
…, JH Sung, EG Shapiro, LA Lockman - Cell …, 1995 - journals.sagepub.com
Treatment and potential cure of lysosomal and peroxisomal diseases, heretofore considered
fatal, has become a reality during the past decade. Bone marrow transplantation, (BMT), …
fatal, has become a reality during the past decade. Bone marrow transplantation, (BMT), …
AS04, an aluminum salt-and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity
AM Didierlaurent, S Morel, L Lockman… - The Journal of …, 2009 - journals.aai.org
Adjuvant System 04 (AS04) combines the TLR4 agonist MPL (3-O-desacyl-4′-monophosphoryl
lipid A) and aluminum salt. It is a new generation TLR-based adjuvant licensed for use …
lipid A) and aluminum salt. It is a new generation TLR-based adjuvant licensed for use …
The future for treatment by bone marrow transplantation for adrenoleukodystrophy, metachromatic leukodystrophy, globoid cell leukodystrophy and Hurler syndrome
W Krivit, LA Lockman, PA Watkins, J Hirsch… - Journal of inherited …, 1995 - Springer
Within the past decade, bone marrow transplantation has been applied to over 200 patients
worldwide with the intention of treating storage diseases. Bone marrow transplantation has …
worldwide with the intention of treating storage diseases. Bone marrow transplantation has …
Long-term effect of bone-marrow transplantation for childhood-onset cerebral X-linked adrenoleukodystrophy
E Shapiro, W Krivit, L Lockman, I Jambaque, C Peters… - The Lancet, 2000 - thelancet.com
… L Lockman, and H Mosér also were the original investigators on this project and have provided
scientific direction. L Lockman … P Aubourg and L Lockman analysed the neurological data …
scientific direction. L Lockman … P Aubourg and L Lockman analysed the neurological data …
Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999
…, NKC Ramsay, KE Dusenbery, DJ Loes, LA Lockman… - Blood, 2004 - ashpublications.org
Cerebral X-linked adrenoleukodystrophy (X-ALD) is a disorder of very-long-chain fatty acid
metabolism, adrenal insufficiency, and cerebral demyelination. Death occurs within 2 to 5 …
metabolism, adrenal insufficiency, and cerebral demyelination. Death occurs within 2 to 5 …
Adrenoleukodystrophy: a scoring method for brain MR observations.
…, AE Stillman, E Shapiro, L Lockman… - American Journal …, 1994 - Am Soc Neuroradiology
PURPOSE To develop a scoring method for brain observations in patients with X-linked
adrenoleukodystrophy. METHODS One hundred seventy-five brain MR scans in 83 male …
adrenoleukodystrophy. METHODS One hundred seventy-five brain MR scans in 83 male …
[HTML][HTML] Hematopoietic stem-cell transplantation in globoid-cell leukodystrophy
…, DJ Loes, K Dusenbery, LA Lockman - … England Journal of …, 1998 - Mass Medical Soc
Background Globoid-cell leukodystrophy is caused by a deficiency of galactocerebrosidase,
which results in progressive central nervous system deterioration. We investigated whether …
which results in progressive central nervous system deterioration. We investigated whether …
Outcome of unrelated donor bone marrow transplantation in 40 children with Hurler syndrome
…, M Crittenden, S Packman, P Kaplan, LA Lockman - 1996 - ashpublications.org
… Hopwood JJ, Muller V, Smithson A, Baggett N: A fluorometric assay using 4-methylumbelliferyl
cy-L-iduronide for the estimation of cy-L-iduronidase activity and the detection of Hurler …
cy-L-iduronide for the estimation of cy-L-iduronidase activity and the detection of Hurler …
Cell-mediated immune responses to a varicella-zoster virus glycoprotein E vaccine using both a TLR agonist and QS21 in mice
N Dendouga, M Fochesato, L Lockman, S Mossman… - Vaccine, 2012 - Elsevier
Lack of adequate cell-mediated immunity (CMI) to varicella-zoster virus (VZV) has been
associated with higher risks of developing herpes zoster (HZ) and associated post-herpetic …
associated with higher risks of developing herpes zoster (HZ) and associated post-herpetic …
