Effect of intra-arterial alteplase vs placebo following successful thrombectomy on functional outcomes in patients with large vessel occlusion acute ischemic stroke: the …

…, A Tomasello, A Dávalos, F Torres, Á Chamorro, L Llull… - Jama, 2022 - jamanetwork.com
… Patients randomized to intra-arterial placebo received a 15-minute infusion of a lyophilized
white powder containing 0.2 mol/L arginine phosphate and 0.01% polysorbate 80, at a pH of …

Acute stroke care is at risk in the era of COVID-19: experience at a comprehensive stroke center in Barcelona

…, C Laredo, V Vera, M Vargas, A Renú, L Llull… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: The purpose of the study is to analyze how the coronavirus disease
2019 (COVID-19) pandemic affected acute stroke care in a Comprehensive Stroke Center…

Administration of uric acid in the emergency treatment of acute ischemic stroke

L Llull, S Amaro, Á Chamorro - Current neurology and neuroscience …, 2016 - Springer
Oxidative stress is one of the main mechanisms implicated in the pathophysiology of inflammatory
and neurodegenerative diseases of the central nervous system (CNS). Uric acid (UA) …

Safety and efficacy of thrombectomy in acute ischaemic stroke (REVASCAT): 1-year follow-up of a randomised open-label trial

…, X Urra, V Obach, A Cervera, S Amaro, L Llull… - The Lancet …, 2017 - thelancet.com
Background The REVASCAT trial and other studies have shown that the neurovascular
thrombectomy improves outcomes at 90 days post stroke. However, whether the observed …

Impact of COVID-19 infection on the outcome of patients with ischemic stroke

…, L Llull, X Ustrell, G Castilho de Oliveira, L Seró… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: We evaluated whether stroke severity, functional outcome, and
mortality are different in patients with ischemic stroke with or without coronavirus disease 2019 …

Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry

…, B Talavera, PC Portela, AN Guillen, X Urra, L Llull… - BMC neurology, 2021 - Springer
Background and purpose Coronavirus disease 2019 (COVID-19) is associated with a small
but clinically significant risk of stroke, the cause of which is frequently cryptogenic. In a large …

Uric acid therapy improves clinical outcome in women with acute ischemic stroke

L Llull, C Laredo, A Renú, B Pérez, E Vila, V Obach… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— It is unknown whether women and men with acute ischemic stroke
respond similar to an antioxidant regimen administered in combination with thrombolysis. …

Relevance of blood–brain barrier disruption after endovascular treatment of ischemic stroke: dual-energy computed tomographic study

…, L Llull, A Lopez, X Urra, J Blasco, L Oleaga… - stroke, 2015 - Am Heart Assoc
Background and Purpose— Computed tomographic (CT) high attenuation (HA) areas after
endovascular therapy for acute ischemic stroke are a common finding indicative of blood–…

Uric acid improves glucose‐driven oxidative stress in human ischemic stroke

S Amaro, L Llull, A Renú, C Laredo, B Perez… - Annals of …, 2015 - Wiley Online Library
Objective A study was undertaken to test in a subgroup reanalysis of the URICO‐ICTUS trial
whether uric acid is superior to placebo in improving the functional outcome in patients with …

Leukocytes, collateral circulation, and reperfusion in ischemic stroke patients treated with mechanical thrombectomy

…, C Laredo, Y Zhao, S Rudilosso, A Renú, L Llull… - Stroke, 2019 - Am Heart Assoc
Background and Purpose— Peripheral immune cells are activated after stroke and may in
turn influence the fate of ischemic brain tissue, thus exerting a dual role in ischemic stroke. We …