Efforts to model pancreatic cancer in mice have focused on mimicking genetic changes found
in the human disease, particularly the activating KRAS mutations that occur in pancreatic …

Background Both gastroesophageal reflux disease and allergy/atopy have been implicated
in the pathogenesis of eosinophilic esophagitis (EoE). There are no prospective studies …

Objectives Pancreatic ductal adenocarcinoma (PDAC) has a dismal 5-year survival rate of 5%.
There is an urgent need for early detection while the tumors are small and surgically …

Purpose: Clear cell renal cell carcinoma (ccRCC) is frequently associated with inactivation
of the von Hippel–Lindau tumor suppressor, resulting in activation of HIF-1α and HIF-2α. The …

Background: Improved diagnostic, predictive, and prognostic biomarkers for pancreatic ductal
adenocarcinoma (PDAC) are urgently needed. Platelet factor 4 (PF4) has been proposed …

KIT mutations are known to occur in∼ 15% of chronic sun damaged cutaneous, mucosal,
and acral melanomas. Melanomas with demonstrated activating mutations in KIT or platelet-…

Structural variation (SV) is typically defined as variation within the human genome that
exceeds 50 base pairs (bp). SV may be copy number neutral or it may involve duplications, …

… A case report with immunohistochemical and in situ hybridization study - Emerson - 2008
- Pediatric Transplantation - Wiley Online Library … Emerson… Emerson …

Same-day turnaround of pathology specimens is desirable in this era of managed care, and
rapid microwave tissue processing produces histologic features of a quality equivalent to …

… Emerson , Lester J. Layfield … The pathologist (LL) reading the frozen section favored a
reactive proliferation, and the surgery was completed at that point. …