User profiles for Leif Østergaard

Leif Østergaard

Center of Functionally Integrative Neuroscience, Department of Clinical Medicine, Aarhus …
Verified email at cfin.au.dk
Cited by 26745

Tracer arrival timing‐insensitive technique for estimating flow in MR perfusion‐weighted imaging using singular value decomposition with a block‐circulant …

O Wu, L Østergaard, RM Weisskoff… - … in Medicine: An …, 2003 - Wiley Online Library
Relative cerebral blood flow (CBF) and tissue mean transit time (MTT) estimates from bolus‐tracking
MR perfusion‐weighted imaging (PWI) have been shown to be sensitive to delay …

The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism

SN Jespersen, L Østergaard - Journal of cerebral blood flow …, 2012 - journals.sagepub.com
Normal brain function depends critically on moment-to-moment regulation of oxygen supply
by the bloodstream to meet changing metabolic needs. Neurovascular coupling, a range of …

Principles of cerebral perfusion imaging by bolus tracking

L Østergaard - Journal of Magnetic Resonance Imaging: An …, 2005 - Wiley Online Library
The principles of cerebral perfusion imaging by the method of dynamic susceptibility contrast
magnetic resonance imaging (DSC‐MRI) (bolus tracking) are described. The MRI signals …

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis

L Østergaard, RM Weisskoff, DA Chesler… - Magnetic resonance …, 1996 - Wiley Online Library
The authors review the theoretical basis of determination of cerebral blood flow (CBF) using
dynamic measurements of nondiffusible contrast agents, and demonstrate how parametric …

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary results

L Østergaard, AG Sorensen, KK Kwong… - Magnetic resonance …, 1996 - Wiley Online Library
This report evaluates several methods to map relative cerebral blood flow (rCBF) by applying
both parametric and non‐parametric techniques to deconvolve high resolution dynamic …

SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and …

L Østergaard - Physiological reports, 2021 - Wiley Online Library
Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs after infection
by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They range from …

Remote ischemic perconditioning as an adjunct therapy to thrombolysis in patients with acute ischemic stroke: a randomized trial

…, TH Cho, AN Redington, HE Bøtker, L Østergaard… - Stroke, 2014 - Am Heart Assoc
Background and Purpose— Remote ischemic preconditioning is neuroprotective in models
of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to …

Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time

AG Sorensen, WA Copen, L Østergaard, FS Buonanno… - Radiology, 1999 - pubs.rsna.org
PURPOSE: To investigate additional information provided by maps of relative cerebral
blood flow in functional magnetic resonance (MR) imaging of human hyperacute cerebral …

Perfusion‐weighted imaging defects during spontaneous migrainous aura

…, AG Sorensen, RM Weisskoff, L Østergaard… - Annals of …, 1998 - Wiley Online Library
Perfusion‐and diffusion‐weighted magnetic resonance imaging was performed during
spontaneous visual auras in four migraineurs. Alterations in relative cerebral blood flow (16–53% …

Acute stroke imaging research roadmap

…, KR Lees, MH Lev, DS Liebeskind, L Ostergaard… - Stroke, 2008 - Am Heart Assoc
The recent “Advanced Neuroimaging for Acute Stroke Treatment” meeting on September 7
and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, …