User profiles for Li-Kai Tsai

Li-Kai Tsai

National Taiwan University Hospital
Verified email at ntuh.gov.tw
Cited by 5147

Neuromuscular disorders in severe acute respiratory syndrome

LK Tsai, ST Hsieh, CC Chao, YC Chen… - Archives of …, 2004 - jamanetwork.com
Objective To delineate and clarify neuromuscular disorders in patients with probable severe
acute respiratory syndrome (SARS). Design Case series with follow-up ranging from 3 …

Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model

LK Tsai, Z Wang, J Munasinghe, Y Leng, P Leeds… - Stroke, 2011 - Am Heart Assoc
Background and Purpose— The migratory efficiency of mesenchymal stem cells (MSC)
toward cerebral infarct after transplantation is limited. Valproate (VPA) and lithium enhance in …

Dysphagia screening decreases pneumonia in acute stroke patients admitted to the stroke intensive care unit

…, YC Chen, CH Chen, SC Tang, LK Tsai… - Journal of the …, 2011 - Elsevier
Dysphagia increases the risk of pneumonia in stroke patients. This study aimed to evaluate
bedside swallowing screening for prevention of stroke-associated pneumonia (SAP) in acute …

[HTML][HTML] The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms

LK Tsai, Y Leng, Z Wang, P Leeds… - …, 2010 - nature.com
Mesenchymal stem cells (MSCs) show high potential for the therapy of several human diseases;
however, the effectiveness of MSC transplantation has been hampered by the relatively …

Contrast-induced encephalopathy after endovascular thrombectomy for acute ischemic stroke

…, KP Lee, CH Chen, PS Sung, YH Lin, CW Lee, LK Tsai… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Contrast-induced encephalopathy (CIE) is a rare and underrecognized
complication after endovascular thrombectomy (EVT) for acute ischemic stroke. This …

Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice

LK Tsai, MS Tsai, CH Ting, H Li - Journal of molecular medicine, 2008 - Springer
Spinal muscular atrophy (SMA) is a progressive disease involving the degeneration of
motor neurons with no currently available treatment. While valproic acid (VPA) is a potential …

Pathogenetical subtypes of recurrent intracerebral hemorrhage: designations by SMASH-U classification system

SJ Yeh, SC Tang, LK Tsai, JS Jeng - Stroke, 2014 - Am Heart Assoc
Background and Purpose— Pathogenetic classification of intracerebral hemorrhage (ICH),
using systems such as SMASH-U (structural vascular lesions, medication, cerebral amyloid …

Valproic acid attenuates blood–brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition

Z Wang, Y Leng, LK Tsai, P Leeds… - Journal of Cerebral …, 2011 - journals.sagepub.com
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, is known to protect against
cerebral ischemia. The effects of VPA on blood–brain barrier (BBB) disruption were investigated …

FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers

Y Leng, Z Wang, LK Tsai, P Leeds, EB Fessler… - Molecular …, 2015 - nature.com
Fibroblast growth factor-21 (FGF-21) is a new member of the FGF super-family and an
important endogenous regulator of glucose and lipid metabolism. It has been proposed as a …

Microangiopathy underlying mixed-location intracerebral hemorrhages/microbleeds: a PiB-PET study

HH Tsai, M Pasi, LK Tsai, YF Chen, BC Lee, SC Tang… - Neurology, 2019 - AAN Enterprises
Objective To test the hypothesis that patients with concomitant lobar and deep intracerebral
hemorrhages/microbleeds (mixed ICH) have predominantly hypertensive small vessel …