Decreased serum ceruloplasmin levels characteristically aggravate nigral iron deposition in Parkinson's disease

L Jin, J Wang, L Zhao, H Jin, G Fei, Y Zhang, M Zeng… - Brain, 2011 - academic.oup.com
In vivo and post-mortem studies have demonstrated that increased nigral iron content in
patients with Parkinson’s disease is a prominent pathophysiological feature. However, the …

Changes in coagulation and tissue plasminogen activator after the treatment of cerebral infarction with lumbrokinase

L Jin, H Jin, G Zhang, G Xu - Clinical Hemorheology and …, 2000 - content.iospress.com
This paper aimed to investigate the effect of lumbrokinase on the anticoagulation and
fibrinolysis in treating cerebral infarction. Lumbrokinase was used in patients with cerebral …

MR imaging of nonalcoholic Wernicke encephalopathy: a follow-up study

C Zhong, L Jin, G Fei - American Journal of Neuroradiology, 2005 - Am Soc Neuroradiology
We investigated the correlation of MR imaging features with the pathological evolution and
prognosis of nonalcoholic Wernicke encephalopathy. A retrospective review and analysis …

[HTML][HTML] Transcriptome analysis reveals the complexity of alternative splicing regulation in the fungus Verticillium dahliae

L Jin, G Li, D Yu, W Huang, C Cheng, S Liao, Q Wu… - Bmc Genomics, 2017 - Springer
Background Alternative splicing (AS) regulation is extensive and shapes the functional
complexity of higher organisms. However, the contribution of alternative splicing to fungal biology …

Mild cognitive impairment in de novo Parkinson's disease: a neuromelanin MRI study in locus coeruleus

…, K Liu, G Fei, C Zhong, M Zeng, L Jin - Movement …, 2019 - Wiley Online Library
Background We aimed to investigate neuromelanin‐sensitive magnetic resonance imaging (NM‐MRI)
features in the locus coeruleus of de novo Parkinson's disease patients with …

[HTML][HTML] Measurement of blood thiamine metabolites for Alzheimer's disease diagnosis

X Pan, G Fei, J Lu, L Jin, S Pan, Z Chen, C Wang… - …, 2016 - thelancet.com
Background Brain glucose hypometabolism is an invariant feature and has significant
diagnostic value for Alzheimer's disease. Thiamine diphosphate (TDP) is a critical coenzyme for …

[HTML][HTML] Combined visualization of nigrosome-1 and neuromelanin in the substantia nigra using 3T MRI for the differential diagnosis of essential tremor and de novo …

L Jin, J Wang, C Wang, D Lian, Y Zhou… - Frontiers in …, 2019 - frontiersin.org
Differentiating early-stage Parkinson's disease (PD) from essential tremor (ET) remains
challenging. In the current study, we aimed to evaluate whether visual analyses of neuromelanin-…

[HTML][HTML] Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer's disease, whereas amyloid deposition does not

…, X Pan, Z Chen, F Zeng, S Pan, H Liu, L Jin… - Alzheimer's research & …, 2018 - Springer
Background The underlying mechanism of brain glucose hypometabolism, an invariant
neurodegenerative feature that tightly correlates with cognitive impairment and disease …

Neuromelanin-sensitive MRI of the substantia nigra: an imaging biomarker to differentiate essential tremor from tremor-dominant Parkinson's disease

…, X Cheng, G Fei, K Liu, M Zeng, C Zhong, L Jin - Parkinsonism & related …, 2019 - Elsevier
Introduction We aimed to evaluate whether neuromelanin-sensitive MRI (NM-MRI) features
in the substantia nigra pars compacta (SNc) were of diagnostic value to differentiate …

Serum microRNA-133b is associated with low ceruloplasmin levels in Parkinson's disease

N Zhao, L Jin, G Fei, Z Zheng, C Zhong - Parkinsonism & related disorders, 2014 - Elsevier
Introduction The cause of low serum ceruloplasmin levels in Parkinson's disease (PD)
remains to be clarified. In this study, we explored serum miR-133b expression to determine …