Assessing mitochondrial dysfunction in cells
MD Brand, DG Nicholls - Biochemical Journal, 2011 - portlandpress.com
… allowing pmf to be equated with Δψ m , although for qualitative studies in the presence of
phosphate, changes in Δψ m tend to be paralleled by similar, but smaller, changes in ΔpH [45]. …
phosphate, changes in Δψ m tend to be paralleled by similar, but smaller, changes in ΔpH [45]. …
[HTML][HTML] Integrating psychological and neurobiological considerations regarding the development and maintenance of specific Internet-use disorders: An Interaction of …
Within the last two decades, many studies have addressed the clinical phenomenon of
Internet-use disorders, with a particular focus on Internet-gaming disorder. Based on previous …
Internet-use disorders, with a particular focus on Internet-gaming disorder. Based on previous …
[HTML][HTML] The Interaction of Person-Affect-Cognition-Execution (I-PACE) model for addictive behaviors: Update, generalization to addictive behaviors beyond internet …
We propose an updated version of the Interaction of Person-Affect-Cognition-Execution (I-PACE)
model, which we argue to be valid for several types of addictive behaviors, such as …
model, which we argue to be valid for several types of addictive behaviors, such as …
[HTML][HTML] FGF23 induces left ventricular hypertrophy
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due
to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
P Haffter, M Granato, M Brand, MC Mullins… - …, 1996 - journals.biologists.com
… A mutation m present in one of the F1 parents was shared by 50% of the fish in the F2 family…
If both parents were heterozygous for m, expected in 1/4 of the crosses, 1/4 of the eggs will …
If both parents were heterozygous for m, expected in 1/4 of the crosses, 1/4 of the eggs will …
Superoxide activates mitochondrial uncoupling proteins
…, A Morrison, S Pickering, JC Clapham, MD Brand - Nature, 2002 - nature.com
Uncoupling protein 1 (UCP1) diverts energy from ATP synthesis to thermogenesis in the
mitochondria of brown adipose tissue by catalysing a regulated leak of protons across the inner …
mitochondria of brown adipose tissue by catalysing a regulated leak of protons across the inner …
[HTML][HTML] Preventing problematic internet use during the COVID-19 pandemic: Consensus guidance
As a response to the COVID-19 pandemic, many governments have introduced steps such
as spatial distancing and “staying at home” to curb its spread and impact. The fear resulting …
as spatial distancing and “staying at home” to curb its spread and impact. The fear resulting …
Association between mitochondrial dysfunction and severity and outcome of septic shock
Background Sepsis-induced multiple organ failure is the major cause of mortality and
morbidity in critically ill patients. However, the precise mechanisms by which this dysfunction is …
morbidity in critically ill patients. However, the precise mechanisms by which this dysfunction is …
[HTML][HTML] Topology of superoxide production from different sites in the mitochondrial electron transport chain
…, JA Buckingham, SJ Roebuck, MD Brand - Journal of Biological …, 2002 - ASBMB
… ), resuspended in standard assay medium containing 120 mm KCl, 5 mmKH 2 PO 4 , 3 mm
Hepes, 1 mm EGTA, and 0.3% BSA (pH 7.2 at 20 C) and kept on ice. Mitochondria were of …
Hepes, 1 mm EGTA, and 0.3% BSA (pH 7.2 at 20 C) and kept on ice. Mitochondria were of …
Explaining entrepreneurial intentions by means of the theory of planned behaviour
… , both the advocates of organizational employment (M=4.92 versus M=4.63, seven‐point
scales) and those of self‐employment (M=4.98 versus M=4.80) believed that their respective …
scales) and those of self‐employment (M=4.98 versus M=4.80) believed that their respective …