Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

Objective: Our objective was to evaluate the published literature and reach a consensus on
the treatment of patients with ACTH-dependent Cushing’s syndrome, because there is no …

… Ki-67 (MiB-1) as the most important proliferation marker is expressed in the G1, S, G2, and
M phases of the cell cycle. In an early study of 1987 (12), biopsy specimens of 31 pituitary …

Object. The goal of this study was to assess the outcome of surgical management in 168
consecutive patients harboring craniopharyngiomas treated between January 1983 and April …

Cushing's disease is caused by corticotroph adenomas of the pituitary. To explore the molecular
mechanisms of endocrine autonomy in these tumors, we performed exome sequencing …

Cancer cells are hallmarked by high proliferation and imbalanced redox consumption and
signaling. Various oncogenic pathways such as proliferation and evading cell death converge …

Background and aim The aim of this study was to illustrate the present role of transsphenoidal
surgery as primary therapy in GH-secreting adenomas, and to compare the results …

Epilepsy surgery is based upon the minute assessment of brain tissue generating epileptic
activity. A number of diagnostic methods are employed in the process of presurgical …

The 13th Acromegaly Consensus Conference was held in November 2019 in Fort
Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and …

Hypercortisolism attributable to hypersecretion of ACTH by a pituitary adenoma is an
uncommon and progressively lethal disease. Because of its rarity, it has been difficult to collect a …